Biology · General Awareness
Vaccination and Immunity
997 Questions
This hub presents questions focused on vaccination and human immunity. It covers essential topics such as herd immunity, non-specific immunity, antigens, and historical vaccine developments. These concepts are crucial for general science sections in medical and civil service exams.
Herd immunity functionsNon-specific immunitySmallpox vaccinationInterferon proteinsAntigen propertiesImmunological amnesia
Vaccination and Immunity Questions
Antivenom injections used for treating snake bite are prepared at
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IVRI, Bareilly
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NDRI, Kamal
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Haffkine Research Institute, Mumbai
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IARI, New Delhi
C
Correct answer
Explanation
Antivenin or anti-snake venom serum is the only drug that can neutralise the snake venom and the victim. It should be injected soon after the bite. They are prepared by immunising horses and mules against the venoms of various types of venomous snakes. These antivenins are prepared in India at Haffkine Institute, Mumbai and Central Research Institute, Kasauli.
So, the correct answer is option C.
How many statements are wrong?
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Colostrum is recommended for the new born, because it is rich in antigen.
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Chikungunya is caused by a gram negative bacterium,
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Tissue culture has proved useful in obtaining virus-free plants.
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Beer is manufactured by distillation of fermented grape juice.
A,B,D
Correct answer
Explanation
Answer is "Three". The correct form of incorrect statements are:
Colostrum is rich in antibodies especially IgA.
Chikungunya is caused alphavirus and not bacteria.
In the fermentation process, beer is obtained from barley while wine is obtained from grapes.
People administered with preformed antibodies get
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active immunity
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innate immunity
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natural immunity
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passive immunity
A
Correct answer
Explanation
The immune system, which is made up of special cells, proteins, tissues, and organs, defends people against germs and microorganisms every day. In most cases, the immune system does a great job of keeping people healthy and preventing infections. But sometimes problems with the immune system can lead to illness and infection. The immune system is the body's defense against infectious organisms and other invaders. Through a series of steps called the immune response, the immune system attacks organisms and substances that invade body systems and cause disease. antibodies can activate a group of proteins called complement that are also part of the immune system. Complement assists in killing bacteria, viruses, or infected cells. All of these specialized cells and parts of the immune system offer the body protection against disease. This protection is called immunity.
So the correct option is 'active immunity'.
Protein released by the host cell in response to attack by a virus is known as
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Antibody
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Antigen
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Interferon
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Immunoglobulin
A
Correct answer
Explanation
Antibodies (also called immunoglobulins) are large proteins. They are found in the blood or other body fluids of vertebrates. Antibodies are the key element in the adaptive immune system. The antibody recognizes a unique part of the foreign target called an antigen. It is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses. Antibody is produced by plasma cells. Antibodies can occur in two physical forms, a soluble form that is secreted from the cell to be free in the blood plasma, and a membrane-bound form that is attached to the surface of a B cell and is referred to as the B-cell receptor (BCR).
So the correct option is 'Antibody'
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Infectious and increased secretion of IgE
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Non- infectious and increased secretions of IgE
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Infectious and increased secretion of IgG
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Non- infectious and increased secretion of IgM
B
Correct answer
Explanation
An allergen is a usually harmless substance capable of triggering a response that starts in the immune system and results in an allergic reaction.
IgE is an immunoglobulin that plays a central role in acute allergic reactions and chronic inflammatory allergic diseases.
Human allergy is caused by a limited number of inhaled small-protein allergens that reproducibly elicit IgE production in susceptible individuals.
So the answer is option B ' Non- infectious and increased secretions of IgE'.
Select the correct statement with respect to diseases and immunisation.
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If due to some reason B and T-Lymphocytes are damaged, the body will not produce antibodies against a pathogen.
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Injection of dead or inactivated pathogens causes passive immunity.
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Certain protozoans have been used to mass produce hepatitis B vaccine.
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Injection of snake antivenom against snake bite is an example of active immunisation.
A
Correct answer
Explanation
Clone of B-cells is called as plasma cells which produce antibodies. Helper T-cells secrete IL-2 (interleukin-2) which stimulate B cells to produce antibodies. For example iInjection of snake antivenom against snake bite that provides artificially acquired passive immunity. Thus, the correct answer is option A.
A substance produced by the host in response to an infection or foreign structure is
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Antigen
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Toxin
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Hormone
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Antibody
D
Correct answer
Explanation
An antibody is a type of proteinaceous substance produced by the body's immune system when it detects harmful substances called antigens. Examples of antigens include microorganisms (bacteria, fungi, parasites and viruses) and chemicals. Each type of antibody is unique and defends the body against one specific type of antigen.
Number of antibodies produced per day during an infection can be
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2 trillion
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20 trillion
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200 trillion
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2000 trillion
B
Correct answer
Explanation
During an active immune response, the body can produce a massive number of antibodies to combat pathogens. The estimate of 20 trillion is generally cited in immunological literature regarding the total number of antibody molecules produced daily.
Which one provides immunity to digestive tract against antigens?
C
Correct answer
Explanation
Immunoglobulin A is an antibody that plays a crucial role in the immune function of mucous membranes. The amount of IgA produced in association with mucosal membranes is greater than all other types of antibody combined. It is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in the blood. Hence it provides immunity to the digestive tract as it is made up of a mucous membrane.
So, the correct answer is 'IgA'.
Which one of the following statements is correct with respect to immunity?
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Preformed antibodies need to be injected to treat the bite by a viper snake
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The antibodies against small pox pathogen are produced by T-lymphocytes
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Antibodies are protein molecules, each of which has four light chains
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Rejection of a kidney graft is the function of B-lymphocytes
A
Correct answer
Explanation
A. Anti-snake venom is made by collecting venom from the snake and injecting small amounts of it usually into a horse. The antibodies that form in the horse blood are then collected and used to treat a snake bite case by injecting directly to the affected person.
B. Antibodies against smallpox are produced by B-lymphocytes.
C. Antibodies contain 2 light chains and 2 heavy chains.
D. Rejection of a kidney graft is a function of T-lymphocytes.
So, the correct answer is, 'Preformed antibodies need to be injected to treat the bite by a viper snake'.
Monoclonal antibodies can be used
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diagnosis, screening and therapy
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in vaccine production
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as enzyme and called enzymes
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in purification and quantification of other molecules
The correct statement about active immunity is:
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It provides immediate relief
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It is long lasting immunity with no side effects
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ATS is used for active immunisation
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It cross the placental barrier
B
Correct answer
Explanation
Active immunity is the antibody response produced by the body when exposed to pathogens, vaccines etc. It is a long lasting immunity and has no side effects as these are WBCs produced by the body.
So, the correct answer is 'it is long lasting immunity with no side effects''
Immunosuppressive drugs possess great risk of infection because
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These act against specific antigen
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These act against all the antigens
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These act on antigenic receptors
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None of the above
D
Correct answer
Explanation
The immunosuppressive drugs are given to treat individuals with autoimmune disorders and to suppress immunity in order prevent host immune responses against antigens on the transplanted organ, thereby avoiding rejection. There are various kinds of immunosuppressive drugs; some drugs like Calcineurin inhibitors act on some of the immune cells which synthesize the receptors for antigen binding. None of the immunosuppressive drugs acts against antigens. However, use of the immunosuppressive drugs pose a risk of infection because they don't specifically inhibit certain cells that cause autoimmunity or transplant rejection, they inhibit the entire immune system making us vulnerable to infections. Thus, the correct answer is option D.
Scientists have developed the first plant based vaccine to combat which virus?
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Swine flu
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Avian flu
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HIV-AIDS
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Zika
D
Correct answer
Explanation
Researchers have utilized plant-based platforms to develop vaccines for various viruses, including Zika, by expressing viral proteins in plants.
Antibodies are produced in
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Human body
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Industries
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Pharmacy
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None of the above
A
Correct answer
Explanation
Antibodies are specialized proteins produced by B-lymphocytes within the human body as part of the adaptive immune response to identify and neutralize pathogens.