Biology
Endocrine and Metabolic Disorders
674 Questions
Endocrine and metabolic disorders focus on diseases caused by hormonal imbalances, such as goitre, diabetes mellitus, and hyperthyroidism. Test takers will find questions related to disease causes, diagnostic tests like Cushing's syndrome indicators, and clinical treatments. This is a crucial biology topic frequently asked in medical entrance and public service commission examinations.
Thyroid gland disordersGoitre causesDiabetes mellitus characteristicsHyperthyroidism treatmentsGrowth hormone deficiency
Endocrine and Metabolic Disorders Questions
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cretinism
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myxoedema
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acromelagy
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dwarfism
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gigantism
B
Correct answer
Explanation
In this condition person becomes sluggish with swelling of the face and hands.
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Only a and b
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Only b and c
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Only a and c
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Only b and d
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Only a and d
A
Correct answer
Explanation
This is the correct option. Addison's disease and diabetes mellitus are caused due to the hyposecretion of hormones. Addison's disease is caused due to hyposecretion of aldosterone hormone. Diabetes mellitus is caused due to hyposecretion of insulin.
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Decrease in the cell concentration of ADP.
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Restriction of ATP production
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Failure of ATP supply to fulfill the demand
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Decrease of triglyceride stores in the body
C
Correct answer
Explanation
The hydrolysis of Adenosine Triphosphate (ATP) provides the energy required by cells for normal function and the intracellular ATP concentration must be maintained for normal function to continue. If the ATP concentration falls, the actin-myosin interactions that generate force within the muscle will not occur effectively.
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Damage caused to ligaments
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Injury to tendons
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Inflammation of synovial membrane
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Deposition of calcium oxalate crystals
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Deposition of uric acid crystals
E
Correct answer
Explanation
Gout causes attacks of pain and swelling in one or more joints.This results from the deposition of uric acid crystals.
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There was no tissue specificity.
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Signalling was not proper.
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PKC cannot be activated.
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All are true.
A
Correct answer
Explanation
cAMP is the hydrophilic molecule which cannot transverse the plasma membrane easily. To overcome the permeability, more hydrophobic derivatives are used resulting that there was no tissue specificity and all cells increased cAMP level. As a result, non-specific and massive responses are formed.
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Respiratory problem
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Urinary problem
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Headache
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All of the above
D
Correct answer
Explanation
As cAMP level decreased, there was no specific signalling to active PKA and PKC. As PKA and PKC are important key enzymes to regulate various metabolic pathways which are inter-related to each other leading to respiratory, urinary and neural disorders.
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Scurvy
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Anemia
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Goitre
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Kwashiorkor
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Diabetes
C
Correct answer
Explanation
This is due to an iodine deficient diet. The treatment of goitre will depend upon the cause of the goitre. If the goitre was due to a deficiency of iodine in the diet , you will be given iodine supplementsorally. This will lead to a reduction in the size of the goitre but often the goitre will not completely resolve.
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Glycogen breakdown in liver.
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Breakdown of structural proteins.
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Dissolution of adipose tissue.
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Excessive secretion of ADH.
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Development of tumor in pituitary gland.
B
Correct answer
Explanation
In the condition of prolonged fasting the structural proteins of the body gets consumed and proteins have large amount of nitrogen in them.
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Hyposecretion of adrenal medulla
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Hyposecretion of adrenal cortex
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Hypersecretion of adrenal cortex
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Hypersecretion of parathyroid
B
Correct answer
Explanation
Hyposecretion of adrenal cortex causes the imbalance of Na and K in the blood. This leads to nervous disorders and convulsions.
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Conn's syndrome
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Addison's disease
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Cushing's syndrome
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Cretinism
C
Correct answer
Explanation
Cushing's syndrome is caused by excessive production of cortisol by the adrenal gland.
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hyper-secretion of corticosteroids
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hyper-secretion of epinephrine and nor-epinephrine
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hyposecretion of glucocorticoids
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hyper-secretion of parathyroid gland
B
Correct answer
Explanation
Hypertension, hyperglycemia, nervousness, sweating and complete exhaustion may occur due to hyper-secretion of epinephrine and nor-epinephrine.
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Cretinism
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Grave's disease
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Hashimoto's disease
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Myxoedema
C
Correct answer
Explanation
Hashimoto's disease is an autoimmune disorder in which the thyroid gland is destroyed by autoimmunity.
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Myxoedema
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Hashimoto's disease
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Grave's disease
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Colloid goitre
C
Correct answer
Explanation
Grave's disease is caused due to hyper-secretion of thyroid.
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Underproduction of hormones by the thyroid gland itself
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Deficient TSH stimulation of thyroid by the pituitary gland
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Underproduction of parathormone
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Overproduction of hormones by the thyroid gland itself
B
Correct answer
Explanation
Deficient TSH stimulation of thyroid by the pituitary gland results into secondary hypothyroidism.
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Only 1 and 3
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Only 2, 3 and 4
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Only 1, 2 and 4
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All of these
B
Correct answer
Explanation
It does not cause Alzheimer's disease.