Biology
Endocrine and Metabolic Disorders
617 Questions
Endocrine and metabolic disorders focus on diseases caused by hormonal imbalances, such as goitre, diabetes mellitus, and hyperthyroidism. Test takers will find questions related to disease causes, diagnostic tests like Cushing's syndrome indicators, and clinical treatments. This is a crucial biology topic frequently asked in medical entrance and public service commission examinations.
Thyroid gland disordersGoitre causesDiabetes mellitus characteristicsHyperthyroidism treatmentsGrowth hormone deficiency
Endocrine and Metabolic Disorders Questions
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Kidney stone
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Hypercholesterolemia
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Ketosuria
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Cirrhosis of liver
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Cholecystitis
B
Correct answer
Explanation
Hypercholesterolemia is a condition whereby an increased cholesterol in blood is caused due to high amount of fat in diet for a prolonged period. It leads to thickening and hardening of arterial wall, which in turn causes narrowing of arteries and thereby blood pressure is increased.
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Cramps and convulsion
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Stunted growth and mental retardation
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Swelling of thyroid gland
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Osteoporosis
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Only stunted growth
B
Correct answer
Explanation
Thyroxine regulates the development of nervous system and the metabolism in foetus. Due to hypothyroidism, maldevelopment of nervous system leads to mental retardation of the child, and as metabolical rate or BMR is decreased in foetus, the growth of the child would be stunted.
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Accelerates protein synthesis
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Retains Ca++ in body
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Retains Ca++ in body and accelerates protein synthesis
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Facilitates growth
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Facilitates growth by retaining Ca++ in body and accelerates protein synthesis
E
Correct answer
Explanation
STH or growth hormone is secreted from anterior lobe of pituitary, and facilitates growth by retaining Ca++ in body and accelerates protein synthesis.
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Wrinkling of face
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Swelling of neck glands
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Bending of legs
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Bulging of eyes
B
Correct answer
Explanation
Goitre is characterised by swollen neck. It is caused due to the deficiency of iodine in the diet.
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Myasthenia gravis
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Systemic lupus erythematosus (SLE)
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Hashimoto's thyroiditis
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Pernicious anaemia
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Insulin-dependent diabetes mellitus
B
Correct answer
Explanation
SLE is a disease involving antibodies to non-organ specific antigens.
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(NZB x W)F1
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MRL-lpr/lpr
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Experimental autoallergic encephalomyelitis
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Thyroiditis induced by early thymectomy and irradiation
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Non-obese diabetic (NOD) mouse
E
Correct answer
Explanation
These mice spontaneously develop an inflammatory attack on the islets of Langerhans.
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Hashimoto's disease
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Primary myxedema
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Graves' disease
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Idiopathic thrombocytopenic purpura
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Autoimmune haemolytic anaemia
C
Correct answer
Explanation
In Graves' disease, there is hyperthyroidism due to stimulating autoantibodies to the TSH receptor, which continuously mimic the effect of TSH but which are not subject to the feedback mechanisms which lower the level of TSH, once sufficient thyroid hormone has been produced.
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hyposecretion of vasopressin
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hyposecretion of insulin
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hyposecretion of thyroxin
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hypersecretion of insulin
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hypersecretion on thyroxin
A
Correct answer
Explanation
Hyposecretion of vasopressin causes Diabetes insipidus.
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Thyroxine
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Adrenaline
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Parathormone
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Progesterone
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Insulin
E
Correct answer
Explanation
This is the correct answer as the deficiency of insulin causes diabetes.
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Hyposecretion from adrenal cortex
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Hypersecretion from adrenal cortex
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Hyposecretion from thyroxin
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Hypersecretion from pituitary gland
A
Correct answer
Explanation
Hyposecretion from adrenal cortex causes Addison's disease, which results in anaemia, hypoglycaemia, nausea, vomiting, diarrhoea, etc.
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hyperglycaemia
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adrenal stress
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adrenal virilism
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adrenal corticoidism
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hypoglycaemia
C
Correct answer
Explanation
If there is an overgrowth of adrenal cortex in a mature woman, she develops certain male characteristics such as a beard, moustache and deep male voice. This condition is known as adrenal virilism.
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Enlargement of thyroid
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Dwarfism and mental retardation
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Swelling of face and hands
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Swelling of neck
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Sluggishness
B
Correct answer
Explanation
Cretinism is a condition characterised by dwarfism and mental retardation in affected children.
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Diabetes insipidus
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Dwarfism
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Acromegaly
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Diabetes mellitus
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Gigantism
A
Correct answer
Explanation
ADH (Anti-diuretic hormone) increases the re-absorption of water from kidney tubules, and its deficiency causes diabetes insipidus.
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Protruded eyes
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Decreased metabolism
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Restlessness
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Shortness of breath
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Rapid heart beat
B
Correct answer
Explanation
Excess of thyroxine secretion causes exophthalmic goitre, and the patient shows a marked increase in metabolic rate and heart beat, shortness of breath, protruded eyes, etc.
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Gigantism
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Acromegaly
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Elevation in blood pressure
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Dwarfism
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Pigmentation
D
Correct answer
Explanation
A child may suffer from dwarfism if there is hyposecretion, i.e., undersecretion of somatotropin or growth hormone (GH).