Biology
Endocrine and Metabolic Disorders
617 Questions
Endocrine and metabolic disorders focus on diseases caused by hormonal imbalances, such as goitre, diabetes mellitus, and hyperthyroidism. Test takers will find questions related to disease causes, diagnostic tests like Cushing's syndrome indicators, and clinical treatments. This is a crucial biology topic frequently asked in medical entrance and public service commission examinations.
Thyroid gland disordersGoitre causesDiabetes mellitus characteristicsHyperthyroidism treatmentsGrowth hormone deficiency
Endocrine and Metabolic Disorders Questions
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gigantic
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cretinism
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myxoedema
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goitre
B
Correct answer
Explanation
Cretinism is caused by severe thyroid hormone deficiency during infancy and early childhood, leading to stunted physical and mental growth. Myxoedema occurs in adults with hypothyroidism. Goitre is thyroid enlargement. Gigantism results from excess growth hormone. The key is 'very early stage of infancy'.
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cretinism
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gigantism
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enlarged thyroid
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reduced thyroid
C
Correct answer
Explanation
Insufficient dietary iodine causes the thyroid gland to enlarge (goitre) as it tries to capture more iodine from the blood to produce thyroid hormones. Cretinism results from iodine deficiency during fetal development. Gigantism is caused by excess growth hormone. The thyroid responds to iodine deficiency by enlarging.
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Diabetes
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Goitre
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Addison's disease
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Slow growth rate
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None of the above
A
Correct answer
Explanation
It is caused by shortage of insulin.
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Precocious puberty
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Obesity
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Gigantism
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Cretinism
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Hyperthyroidism
C
Correct answer
Explanation
An overproduction of somatotropin before adolescence, causes gigantism.
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myxedema
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cretinism
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exopthalmic goiter
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myopia
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hypermetropia
A
Correct answer
Explanation
Hypothyroidism during the adult years causes myxedema. Myxedema is the swelling of the skin and underlying tissues giving a waxy consistency, typical of patients with underactive thyroid glands.
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Gonadal hormones
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Gonadotropins
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Thyroid hormones
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Adrenal hormones
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Insulin
C
Correct answer
Explanation
Cretinism is a clinical condition which is associated with hyposecretion of certain hormones during the growing years; these hormones are thyroid hormones.
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anterior lobe of pituitary
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posterior lobe of pituitary
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intermediate lobe of pituitary
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thyroid
B
Correct answer
Explanation
Diabetes insipidus is caused by deficiency of ADH (antidiuretic hormone) or vasopressin, which is produced in the hypothalamus and stored/released by the posterior pituitary gland. The anterior pituitary produces different hormones (GH, TSH, ACTH, FSH, LH, prolactin).
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gigantic
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cretinism
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myxoedema
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goitre
B
Correct answer
Explanation
Cretinism results from severe hypothyroidism (thyroid hormone deficiency) during early infancy, causing stunted growth and intellectual disability. Gigantism is from excess GH in childhood. Myxoedema is hypothyroidism in adults. Goitre is thyroid enlargement (can be from deficiency or excess).
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endocrine system
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circulatory system
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nervous system
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excretory system
C
Correct answer
Explanation
In animal cells, peroxisomes are involved in synthesis of plasmalogen.
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Grave's disease
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Hashimoto's thyroiditis
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Myasthania gravis
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Both 1 and 2
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Both 2 and 3
B
Correct answer
Explanation
Hashimotos thyroiditis is due to TSH stimulation-blocking antibody, which blocks activation of TSH hormone and subsequently bring damage and atrophy of thyroid gland.
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Scurvy
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Rickets
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Beri beri
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Goitre
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Pellagra
D
Correct answer
Explanation
Swollen neck is caused due to goitre.
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Diabetes insipidus
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Diabetes mellitus
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Hypoglycemia
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Glycogenesis
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Glycogenolysis
B
Correct answer
Explanation
Diabetes mellitus is a chronic disease with abnormally high levels of the sugar glucose in the blood. It is assciated with loss of glucose through urine.
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1 and 2
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1 and 4
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2 and 3
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3 and 4
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4 and 5
B
Correct answer
Explanation
Adrenal virilism is the development of male secondary sex characteristics caused by male sex hormones, called androgens, excessively produced by the adrenal gland. Conn's syndrome is a disease of the adrenal glands involving excess production of a hormone, called aldosterone.
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Hypoglycemia
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Hypocalcemia
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Myxoedema
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Diabetes insipidus
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Simmond’s disease
B
Correct answer
Explanation
Hypocalcemia is caused due to hyposecretion of paratharmone.
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1 and 3
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2 and 5
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3 and 5
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4 and 5
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5 and 6
C
Correct answer
Explanation
Grave’s disease is caused due to hyper-secretion of thyroxine. Plummer’s disease is caused due to hyper-secretion of thyroxine.