Multiple choice Phenylketonuria is an example of an inborn error of metabolism. This error refers to Hormonal over production Atrophy of endocrine glands Inherited lack of an enzyme Nondisjunction Reveal answer Fill a bubble to check yourself C Correct answer Explanation Phenylketonuria is caused by a defect in the gene that helps create the enzyme phenylalanine hydroxylase. The inherited lack of this enzyme leads to the toxic buildup of the amino acid phenylalanine.