Biology

Human Immunity and Blood

2,096 Questions

Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.

Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology

Human Immunity and Blood Questions

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Blood corpuscles containing both A and B antigens are mixed with another blood serum. The blood corpuscles agglutinated. Blood serum belongs to blood group

  1. A

  2. B

  3. AB

  4. O.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

If blood corpuscles with both A and B antigens (AB group) are agglutinated by a serum, that serum must contain both anti-A and anti-B antibodies, which is characteristic of blood group O.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

For safe blood transfusion

  1. Donor's RBC should not contain antibodies against recipient's serum

  2. Recipient's serum should not contain antigens against donor's antibodies

  3. Recipient's serum should not contain antibodies against RBC of donors

  4. Recipient's RBC should not contain antibodies against donor's antigens.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

For a safe transfusion, the recipient's plasma must not contain antibodies that react with the antigens present on the donor's red blood cells.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

A mismatch during transfusion of blood causes

  1. Agglutination

  2. Erythroblastosis

  3. Haemopoies

  4. None of the above.
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

A mismatch in blood transfusion leads to the binding of antibodies to antigens on the donor's red blood cells, causing them to clump together, a process known as agglutination.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Assertion. Blood group 'O' has both anti-A and anti-B antibodies
Reason. It does not have any antigen

  1. A

  2. B

  3. C

  4. D.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Blood group O lacks both A and B antigens on its red blood cells, which is why it contains both anti-A and anti-B antibodies in the plasma. Both the assertion and reason are correct and the reason explains the assertion.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Which blood group is universal donor

  1. $O^+$
  2. $O^-$
  3. $AB^+$
  4. $AB^-$.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Blood group O negative (O-) is considered the universal donor because it lacks A, B, and Rh antigens on the surface of its red blood cells. This prevents the recipient's immune system from attacking the donated blood.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

What is true of blood group B

  1. The person can form antibody b

  2. The person cannot form antibody b

  3. The person cannot be given blood of 'O' group

  4. The person can receive blood of AB group.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Individuals with blood group B possess B antigens on their red blood cells and naturally produce anti-A antibodies. They do not produce anti-B antibodies, as doing so would cause their own blood to agglutinate.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

The natural antibodies in the plasma of a person with blood group 'O' is

  1. anti-A

  2. anti-B

  3. anti-A and anti-B

  4. anti-B and anti-D

  5. anti-D.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

People with blood group O lack both A and B antigens on their red blood cells. Consequently, their plasma contains both anti-A and anti-B antibodies.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Clumping of RBC may occur when blood of one person is mixed with serum or blood of another person. This is due to

  1. Antigen-antibody reaction

  2. Antitoxin-antibody reaction

  3. Antigen-antigen reaction

  4. Antibody-antibody reaction
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

The RBC membrane contains either antigen A or antigen B, or both Antigen A and B or no antigen at all, accordingly the blood is classified as blood group A , B , AB and O respectively. The blood plasma of blood group A will have antibodies for B, that of B will have antibodies for A,  that of AB will have non, while that of O will have both the antibodies. If blood is transfused at random this will lead to antigen-antibody reaction - like if A is the blood group of the recipient while the blood group of the donor happens to be B, this will lead to clumping of the RBCs.

So, the correct answer is 'Antigen-antibody reaction'

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Anti-A and Anti-B antibodies are not found in which of the following blood group?

  1. AB

  2. A

  3. O

  4. B
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

The cell membrane of RBCs in AB blood group contain both antigen A as well as antigen B therefore the blood plasma does not contain antibody A and Antibody B, to prevent the coagulation of blood cells due to antigen-antibody reactions.

So, the correct answer is 'AB'

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

A child's blood group is `O'. The parents blood groups cannot be

  1. AB and 0

  2. B and 0

  3. A and B

  4. A and A
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

A child with blood group O has the genotype ii, meaning they must inherit one i allele from each parent. Parents with AB (genotype IAIB) cannot pass on an i allele, so they cannot have an O child.