Biology
Human Immunity and Blood
2,051 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
Which of the following is a type of cancer that originates in the cells of the blood-forming tissues?
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Lung cancer
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Breast cancer
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Leukemia
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Colon cancer
C
Correct answer
Explanation
Leukemia is a type of cancer that originates in the cells of the blood-forming tissues, such as the bone marrow and lymph nodes.
Which of the following is a type of cell that is responsible for the formation of new blood cells?
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Hematopoietic Stem Cells
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Neural Stem Cells
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Mesenchymal Stem Cells
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Adipose Stem Cells
A
Correct answer
Explanation
Hematopoietic stem cells are a type of cell that is responsible for the formation of new blood cells.
Which cytokine is primarily produced by Th1 cells?
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Interleukin-4 (IL-4)
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Interleukin-10 (IL-10)
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Interferon-gamma (IFN-γ)
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Interleukin-17 (IL-17)
C
Correct answer
Explanation
Th1 cells are known for producing IFN-γ, which is a key cytokine involved in cell-mediated immunity and defense against intracellular pathogens.
Which cytokine is primarily produced by Th17 cells?
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Interleukin-4 (IL-4)
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Interleukin-10 (IL-10)
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Interleukin-17 (IL-17)
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Interferon-gamma (IFN-γ)
C
Correct answer
Explanation
Th17 cells are known for producing IL-17, which is a cytokine involved in promoting inflammation and defense against extracellular bacteria and fungi.
Which cytokine is primarily produced by Tregs?
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Interleukin-4 (IL-4)
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Interleukin-10 (IL-10)
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Interferon-gamma (IFN-γ)
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Interleukin-17 (IL-17)
B
Correct answer
Explanation
Tregs are known for producing IL-10, which is a cytokine that suppresses immune responses and promotes immune tolerance.
Which cytokine is primarily produced by Th22 cells?
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Interleukin-4 (IL-4)
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Interleukin-10 (IL-10)
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Interleukin-22 (IL-22)
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Interferon-gamma (IFN-γ)
C
Correct answer
Explanation
Th22 cells are known for producing IL-22, which is a cytokine involved in promoting tissue repair and defense against extracellular bacteria and fungi.
What is the role of follicular helper T cells (Tfh) in the immune system?
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To activate cytotoxic T cells
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To promote antibody production by B cells in germinal centers
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To regulate inflammatory responses
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To directly kill infected cells
B
Correct answer
Explanation
Tfh cells play a crucial role in promoting antibody production by B cells in germinal centers, which is essential for the generation of high-affinity antibodies.
Which cytokine is primarily produced by Tfh cells?
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Interleukin-4 (IL-4)
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Interleukin-10 (IL-10)
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Interferon-gamma (IFN-γ)
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Interleukin-21 (IL-21)
D
Correct answer
Explanation
Tfh cells are known for producing IL-21, which is a cytokine that promotes antibody production by B cells and the formation of germinal centers.
Which cytokine is primarily produced by Tr1 cells?
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Interleukin-4 (IL-4)
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Interleukin-10 (IL-10)
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Interferon-gamma (IFN-γ)
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Interleukin-17 (IL-17)
B
Correct answer
Explanation
Tr1 cells are known for producing IL-10, which is a cytokine that suppresses immune responses and promotes immune tolerance.
Which transcription factor is essential for the development of Th2 cells?
B
Correct answer
Explanation
GATA-3 is a transcription factor that is essential for the development and function of Th2 cells, which are involved in humoral immunity.
What is the role of retinoic acid (RA) in the differentiation of T helper cells?
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It promotes the differentiation of Th1 cells
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It promotes the differentiation of Th2 cells
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It promotes the differentiation of Th17 cells
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It promotes the differentiation of Tregs
D
Correct answer
Explanation
RA is a metabolite of vitamin A that plays a role in promoting the differentiation of Tregs, which are involved in immune tolerance.
Which type of immune cell is responsible for producing antibodies?
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B cells
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T cells
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Natural killer cells
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Macrophages
A
Correct answer
Explanation
B cells are responsible for producing antibodies, which are proteins that recognize and bind to specific antigens.
What is the role of T cells in the immune response?
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To produce antibodies
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To destroy infected cells
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To activate B cells
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All of the above
D
Correct answer
Explanation
T cells play a crucial role in the immune response by destroying infected cells, activating B cells, and providing help to other immune cells.
Which type of immune disorder is characterized by the production of autoantibodies?
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Allergy
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Autoimmune disease
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Immunodeficiency
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Hypersensitivity
B
Correct answer
Explanation
Autoimmune diseases are characterized by the production of autoantibodies, which are antibodies that target the body's own tissues.
What is the role of the MHC molecules in the immune response?
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To present antigens to T cells
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To activate B cells
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To produce antibodies
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To destroy infected cells
A
Correct answer
Explanation
MHC molecules present antigens to T cells, which allows the T cells to recognize and respond to the antigens.