Biology
Human Immunity and Blood
2,096 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
Which type of immune response is characterized by a delayed hypersensitivity reaction?
-
Cell-mediated immunity
-
Humoral immunity
-
Innate immunity
-
Adaptive immunity
A
Correct answer
Explanation
Cell-mediated immunity, involving the activation of T cells and macrophages, is responsible for delayed hypersensitivity reactions, such as those seen in tuberculin skin tests.
Which type of immune response is responsible for generating memory cells?
-
Cell-mediated immunity
-
Humoral immunity
-
Innate immunity
-
Adaptive immunity
D
Correct answer
Explanation
Adaptive immunity, involving the activation and differentiation of lymphocytes, is responsible for generating memory cells that provide long-term protection against pathogens.
Which of the following is not a type of cancer?
-
Carcinoma
-
Sarcoma
-
Leukemia
-
Myeloma
D
Correct answer
Explanation
Myeloma is a type of blood cancer, while carcinoma, sarcoma, and leukemia are all types of solid tumors.
Which type of immune cell is primarily responsible for the maternal immune response during pregnancy?
-
T cells
-
B cells
-
Natural killer cells
-
Macrophages
A
Correct answer
Explanation
T cells, particularly regulatory T cells (Tregs), play a key role in maintaining immune tolerance and preventing the rejection of the fetus during pregnancy.
Which type of fetal antigen is primarily responsible for inducing alloimmune thrombocytopenia?
-
Human platelet antigen-1a (HPA-1a)
-
Human platelet antigen-5b (HPA-5b)
-
Human platelet antigen-9 (HPA-9)
-
Human platelet antigen-15 (HPA-15)
A
Correct answer
Explanation
HPA-1a is the most common fetal platelet antigen that can induce alloimmune thrombocytopenia in pregnant women who lack this antigen.
Which type of immune cell is primarily responsible for attacking and destroying infected cells during pregnancy?
-
Natural killer cells
-
Cytotoxic T cells
-
Helper T cells
-
B cells
A
Correct answer
Explanation
Natural killer cells play a crucial role in the innate immune response during pregnancy by recognizing and destroying infected cells, including those infected with viruses or bacteria.
What is the name of the condition in which the maternal immune system produces antibodies against fetal red blood cell antigens, leading to hemolytic disease of the newborn (HDN)?
-
Alloimmune hemolytic anemia
-
Alloimmune thrombocytopenia
-
Pre-eclampsia
-
Gestational diabetes
A
Correct answer
Explanation
Alloimmune hemolytic anemia is a condition in which the maternal immune system produces antibodies against fetal red blood cell antigens, leading to the destruction of fetal red blood cells and potential complications for the fetus.
Which fetal red blood cell antigen is primarily responsible for inducing alloimmune hemolytic anemia?
-
Rhesus (Rh) factor
-
Kell antigen
-
Duffy antigen
-
Kidd antigen
A
Correct answer
Explanation
The Rh factor is the most common fetal red blood cell antigen that can induce alloimmune hemolytic anemia in pregnant women who lack this antigen.
What is the recommended treatment for leukemia in children?
-
Chemotherapy
-
Radiation therapy
-
Stem cell transplant
-
All of the above
D
Correct answer
Explanation
The recommended treatment for leukemia in children includes chemotherapy, radiation therapy, stem cell transplant, and a combination of these approaches.
Which type of cancer is characterized by the uncontrolled growth of cells in the blood-forming tissues?
-
Leukemia
-
Lymphoma
-
Myeloma
-
Hodgkin's Lymphoma
A
Correct answer
Explanation
Leukemia is a type of cancer that affects the blood-forming tissues, including the bone marrow and lymph nodes.
What is the name of the treatment modality that uses the body's immune system to fight cancer?
-
Immunotherapy
-
Chemotherapy
-
Radiotherapy
-
Surgery
A
Correct answer
Explanation
Immunotherapy is a treatment modality that uses the body's immune system to fight cancer by enhancing its ability to recognize and attack cancer cells.
Which type of cancer is characterized by the uncontrolled growth of cells in the blood-forming tissues?
-
Leukemia
-
Lymphoma
-
Myeloma
-
All of the above
D
Correct answer
Explanation
Leukemia, lymphoma, and myeloma are all types of cancer that arise from the blood-forming tissues. Leukemia affects the white blood cells, lymphoma affects the lymph nodes and other lymphoid tissues, and myeloma affects the plasma cells.
Which of the following is a laboratory finding associated with neonatal sepsis?
-
Leukocytosis
-
Elevated C-reactive protein (CRP)
-
Positive blood culture
-
All of the above
D
Correct answer
Explanation
Leukocytosis, elevated CRP, and positive blood culture are all laboratory findings associated with neonatal sepsis.
Which of the following is a laboratory finding associated with neonatal meningitis?
-
Leukocytosis
-
Elevated C-reactive protein (CRP)
-
Positive cerebrospinal fluid (CSF) culture
-
All of the above
D
Correct answer
Explanation
Leukocytosis, elevated CRP, and positive CSF culture are all laboratory findings associated with neonatal meningitis.
Which of the following is a laboratory finding associated with neonatal pneumonia?
-
Leukocytosis
-
Elevated C-reactive protein (CRP)
-
Positive chest X-ray
-
All of the above
D
Correct answer
Explanation
Leukocytosis, elevated CRP, and positive chest X-ray are all laboratory findings associated with neonatal pneumonia.