Biology

Human Immunity and Blood

2,051 Questions

Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.

Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology

Human Immunity and Blood Questions

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

In ABO system of blood grouping, transfusion is not possible from

  1. A to AB

  2. B to AB

  3. O to AB

  4. A to O.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Transfusion from A to O is not possible because O individuals have anti-A antibodies in their plasma, which would react with the A antigens on the donor's red blood cells.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

In case of emergency (e.g., serious accident with great blood loss) which blood group could be safely transfused

  1. AB $Rh^-$
  2. O $Rh^+$
  3. AB $Rh^+$
  4. O $Rh^-$.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Individuals with O Rh-negative blood are universal donors because their red blood cells lack both A and B antigens and the Rh factor, minimizing the risk of an immune reaction in the recipient.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Person with AB blood group can

  1. Not receive universally

  2. Universally donate

  3. Universally receive

  4. Receive only from O.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

People with blood group AB possess both A and B antigens on their red blood cells but lack anti-A and anti-B antibodies in their plasma, allowing them to receive blood from any ABO group.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Donor X and recipient Y belong to same blood group. Transfusion has led to RBC agglutination because

  1. X is $Rh^+$, Y is $Rh^-$
  2. X is $Rh^-$, Y is $Rh^+$
  3. Both are $Rh^+$
  4. Both are $Rh^-$.
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Agglutination occurs when the recipient has antibodies against the donor's antigens. An Rh-negative recipient (Y) can develop anti-Rh antibodies if exposed to Rh-positive blood from the donor (X).

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Blood group B means the person

  1. Can form antibody for B

  2. Cannot form antibody for B

  3. Can receive blood of AB group

  4. Cannot receive blood group O.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Individuals with blood group B have B antigens on their red blood cells; therefore, they do not produce anti-B antibodies, as doing so would cause their own blood to agglutinate.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

Blood corpuscles containing both A and B antigens are mixed with another blood serum. The blood corpuscles agglutinated. Blood serum belongs to blood group

  1. A

  2. B

  3. AB

  4. O.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

If blood corpuscles with both A and B antigens (AB group) are agglutinated by a serum, that serum must contain both anti-A and anti-B antibodies, which is characteristic of blood group O.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

For safe blood transfusion

  1. Donor's RBC should not contain antibodies against recipient's serum

  2. Recipient's serum should not contain antigens against donor's antibodies

  3. Recipient's serum should not contain antibodies against RBC of donors

  4. Recipient's RBC should not contain antibodies against donor's antigens.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

For a safe transfusion, the recipient's plasma must not contain antibodies that react with the antigens present on the donor's red blood cells.

Multiple choice bio-chemistry immunity and blood groups blood group blood groups and compatibility advance blood groups and transfusion compatibility of blood groups

A mismatch during transfusion of blood causes

  1. Agglutination

  2. Erythroblastosis

  3. Haemopoies

  4. None of the above.
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

A mismatch in blood transfusion leads to the binding of antibodies to antigens on the donor's red blood cells, causing them to clump together, a process known as agglutination.