Tag: commercial applications of biotechnology

The therapeutic techniques used to treat deleterious phenotypic effects of a genetic defect especially without altering the genetic makeup of the germplasm of the individual is known as Euphenics. Therefore it is the improvement of phenotypic effect in humans after their birth by genetic engineering. Hence option B is correct.

Har Gobind Khorana is widely recognized for his pioneering work in deciphering the genetic code and synthesizing the first artificial gene, which laid the foundation for genetic engineering.

DNA technology, specifically recombinant DNA technology, is the primary method used to introduce desirable changes into the genotype of an organism.

Transgenic mice are being formed for use in testing the safety of before they are used they are used on human beings. They are being used to test the safety of the polio vaccine. The first transgenic cow. Rosie produced human protein enriched milk (2.4 gms per litre). The milk contained the human alphalactalbumin. It is a more balanced product for human babies than natural cow-milk. Bulls with more power are produced by animal breeding not by genetic engineering. So, the correct answer is 'Transgenic mice for testing safety of polio vaccine before use in humans'.

A xenobiotic is a foreign chemical substance found within an organism that is not normally naturally produced by or expected to be present within that organism. The term xenobiotics is often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because xenobiotics are understood as substances foreign to an entire biological system, i.e., artificial substances, which did not exist in nature before their synthesis by humans. 

Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium. It naturally occurs in the soil, and about 30% of strains can fix nitrogen in anaerobic conditions.

The basic process of recombinant DNA technology revolves around the activity of DNA in the synthesis of protein. By intervening in this process, scientists can change the nature of the DNA and of the gene make-up of an organism. By inserting genes into the genome of an organism, the scientist can induce the organism to produce a protein it does not normally produce. The genes used in DNA technology are commonly obtained from host cells or organisms called as gene libraries. A gene library is a collection of cells identified as harbouring a specific gene. For example, E. coli cells can be stored with the genes for human insulin in their chromosomes. Vaccines represent another application of recombinant DNA technology. For instance, the hepatitis B vaccine now in use is composed of viral protein manufactured by yeast cells, which have been recombined with viral genes. 

Genetic engineering, also called as genetic modification, is the direct manipulation of an organism's genome using biotechnology. New DNA is inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA and then inserting this construct into the host organism. Genetic engineering techniques have been applied in numerous fields including research, agriculture, industrial biotechnology, and medicine. Enzymes used in laundry detergent and medicines such as insulin and human growth hormone are now manufactured in GM cells, experimental GM cell lines and GM animals such as mice or zebrafish are being used for research purposes, and genetically modified crops have been commercialized.