Tag: genetics of the future

Questions Related to genetics of the future

An example of gene therapy is 

  1. Production of injectible hepatitis B vaccine

  2. Production of vaccines in food crops like potatoes which can be eaten.

  3. Introduction of gene for adenosine deaminase in persons suffering from SCID

  4. Production of test tube babies by artificial insemination and implantation of fertilised eggs.


Correct Option: C
Explanation:

Gene therapy is a collection of methods that allows correction of gene defect that has been diagnosed in a child  for adenosine deaor embryo. An example of gene therapy is the introduction  of geneminase in persons suffering from ADA deficiency, a disorder caused due to the deletion of gene for adenosine deaminase. In some patients , it can be cured by bone marrow transplantation whereas in some by the enzyme replacement therapy

So, the correct option is 'introduction of gene for adenosine deaminase in persons suffering from SCID'

Gene can therapy can be referred to as  

  1. Pre-clinical testing for inherited diseases in newborns

  2. Treatment of diseases caused by genetic defect

  3. Genetic engineering using rDNA technology

  4. Cancer treatment using in-vitro cultured stem cells


Correct Option: B
Explanation:

Gene therapy is a collection of methods, that allows correction of gene defect that has been diagnosed in a child/embryo. Correcting of a genetic defect involves delivery of a normal gene into the individual or embryo to take over the function of and compensate for the non-functional gene.

What might be an advantage of beginning gene therapy prior to birth? 

  1. This would give the body plenty of time to utilize the new genes.

  2. The body would not reject it as it has not yet recognized 'self'.

  3. The cells being extremely young. are more receptive of gene therapy.

  4. There probably is not any advantage.


Correct Option: B
Explanation:

Gene therapy is a newly emerging branch of biotechnology with tremendous results. It is basically used for correcting genetic disorders. In gene therapy, normal genes are introduced in the cells to replace the missing genes or defective genes. 

Early gene therapy has been proved to be more effective in treating certain brain diseases in humans. They have also shown exemplary results in mice.  
When a child is born, he has its innate immunity, which does not allow any foreign body to settle into its own body easily. But before birth, it has not yet recognized itself, so therapy would be easily accepted.
So the correct answer is B.

A genetic disorder can be cured through

  1. rDNA technology

  2. Embryo transfer

  3. Gene therapy

  4. All of these.


Correct Option: C
Explanation:

Gene therapy is a collection of methods, that allows correction of a gene defect that has been diagnosed in a child embryo.

The method of correcting the defective genes is called

  1. genetic engineering

  2. gene therapy

  3. somatic hybridization

  4. protoplast fusion


Correct Option: B
Explanation:
The use of bioengineered cells and biological techniques to treat human genetic disorder is known as gene therapy. Gene therapy is the transfer of a normal gene into body cells to correct the genetic defect. It can be used to treat genetic diseases like sickle cell anaemia and SCID.
The SCID patients have no functioning t lymphocytes and one treated with injections of the white blood cells that have been engineered to carry the normal ADA alleles.
So, the correct option is 'gene therapy'

Which kind of therapy was given in $1990$ to a four-year-old girl with Adenosine Deaminase(ADA) deficiency?

  1. Gene therapy

  2. Chemotherapy

  3. Immunotherapy

  4. Radiation therapy


Correct Option: A
Explanation:

First successful gene transfer in human was performed by F.Anderson. Ashi Disilva a 4-year girl was treated by replacing ADA gene in lymphocytes.

The girl was suffering from Severe Combined Immunodeficiency (SCID). Gene therapy was used for the treatment of ADA deficiency.
So, the correct option is 'Gene therapy'.

Recombinant DNA technology developed during

  1. 1970s

  2. 1980s

  3. 1990s

  4. 2000s


Correct Option: A
Explanation:
The correct option is A
rDNA technology is the way in which genetic material from one organism is artificially introduced into the genome of another organism and then replicated and expressed by other organism. It was advanced by the collaboration of stanley cohen and Herbert Boyer in $1972$.

Science of engineering and technology which is applied to life sciences is

  1. Biotechnology

  2. Genetic engineering

  3. Pathology

  4. Conchology


Correct Option: A
Explanation:

  • Biotechnology is the science of engineering and technology for industrial and other purposes, especially the genetic manipulation of microorganisms for the production of antibiotics, hormones, etc. 
  • Bioengineering is the application of the principles of engineering and natural sciences to tissues, cells and molecules. It improves the functions of plants and animals.

So, the correct answer is 'Biotechnology'.

Which is the first cloned animal?

  1. Dog

  2. Molly

  3. Dolly sheep

  4. Polly sheep


Correct Option: C
Explanation:

Dolly was a female domestic sheep, and the first mammal to be cloned from an adult somatic cell, using the process of nuclear transfer. Ian Wilmut developed Dolly.

What is true of reverse genetics

  1. Gene therapy

  2. Gene replacement

  3. Identification of gene from map position

  4. Deletion of genes and studying the effect


Correct Option: C
Explanation:

Reverse genetics is a method that is used to help understand the function of a gene by analyzing the phenotypic effects of specific engineered gene sequences. Reverse genetics usually proceeds in the opposite direction of so-called forward genetic screens of classical genetics. The goal in reverse genetics is Identification of gene from map position.

So, the correct answer is 'Identification of gene from map position.'