Chemistry · Biology

Pharmacology and Therapeutics

1,643 Questions

Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.

Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests

Pharmacology and Therapeutics Questions

Multiple choice

A lachrymator causes watering of the eyes. Which among the following acids is a powerful lachrymator?

  1. Fluorosulphuric acid

  2. Nitrosylsulphuric acid

  3. Chlorosulphuric acid

  4. Peroxymonosulphuric
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Chlorosulphuric acid (HSO3Cl) is a distillable, colourless liquid that should be handled with care. It is a hygroscopic and a powerful lachrymator. It is used to prepare sulphonic acids, which are useful in detergents and as chemical intermediates.

Multiple choice

Cyclophosphamide is a commonly used drug in anticancer therapy. Which of the following statements is FALSE regarding this drug?

  1. The structure is metabolised to release acrolein.

  2. It cannot be taken orally.

  3. It is comparitively non-toxic.

  4. It acts as a prodrug in the body.

  5. It is mainly used in the treatment of lymphomas.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The drug is called cyclophosphamide. It can be taken orally . Since it is a prodrug, it is not toxic to the gut wall when taken orally.

Multiple choice

Which of the following agents is NOT immunosuppressive?

  1. Levamisole

  2. Corticosteroid

  3. Thalidomide

  4. Aspirin

  5. Total lymphoid irradiation
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

This is an anti-inflammatory drug. Aspirin is part of a group of medications called non-steroidal anti-inflammatory drugs (NSAIDs) and has antipyretic, anti-inflammatory and analgesic properties but does not affect immunity. Aspirin inhibits the enzyme, cyclooxygenase.

Multiple choice

What does intake of disulfiran lead to?

  1. Removal of toxic alcoholic substances from the body

  2. Vomiting

  3. Development of distaste for alcohol

  4. Increase in acetaldehyde level of blood
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Disulfiran increases acetaldehyde level of the blood which causes suffering like tachycardia, hypertension. headache and increase in the rate of respiration.

Multiple choice

Which of the following drugs belonging to ansamycin family has received orphan drug status?

  1. Gelandamycin

  2. Rifaximin

  3. Rifampin

  4. Herbimycin
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Rifaximin is used to treat traveler's diarrhoea, irritable bowel syndrome and hepatic encephalopathy, for which it received orphan drug status from the U.S. Food and Drug Administration in 1998. An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition. Rifaximin has orphan drug status for the treatment of hepatic encephalopathy, which is a rare disease.

Multiple choice

Which of the following hallucinogens is the most dangerous?

  1. Piperidine

  2. Psilocyabin

  3. LSD

  4. Marihuana
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

LSD is the most dangerous hallucinogen. Being colorless, tasteless and odorless, it can be incorporated illegally into food items and gums of stamps and envelopes to commit crimes.