Chemistry ยท Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
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Seoltamivir
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Oseltamivir
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Oseltamivries
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Oseltamonisicivir
B
Correct answer
Explanation
Oseltamivir is the correct answer. Tamiflu is the brand name for the antiviral drug oseltamivir phosphate, which is used to treat influenza A and B. Options A, C, and D are misspellings or incorrect variants of the drug name.
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Cross over trial
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Stratified randomisation
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Double dummy
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It is not possible to double blind this trial
C
Correct answer
Explanation
The double-dummy technique is used when comparing treatments with different routes or appearances. Each participant receives both active treatments and their corresponding placebos. For nasal spray vs oral tablet, participants would get both active spray + placebo tablet OR placebo spray + active tablet.
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phase 1
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phase 2a
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phase 2b
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phase 3
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phase 4
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phase 0
F
Correct answer
Explanation
Phase 0 (exploratory IND) is a first-in-human trial conducted under limited human exposure, with no therapeutic intent. It's used to gather preliminary pharmacokinetic and pharmacodynamic data before traditional Phase I trials. The FDA issued specific guidance on these studies in 2006.
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You wouldn't - this is unethical
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Only in children over the age of 13
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Only if the product will only be used in children
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Only if a specialist panel agrees it is necessary
A
Correct answer
Explanation
Conducting pharmacokinetic trials in healthy children violates fundamental bioethical principles as children are a vulnerable population unable to give informed consent. Clinical trials in children should only involve patients who may benefit from the treatment. Age restrictions (option B) do not address the core ethical violation, and specialist approval (option D) cannot override basic ethical prohibitions.
A
Correct answer
Explanation
Asthma medications include quick-relief inhalers (bronchodilators) for immediate symptom relief and controller medications (inhaled corticosteroids) for long-term prevention. Different types serve different purposes in asthma management.
B
Correct answer
Explanation
False - Many OTC medications (like acetaminophen, aspirin, antihistamines) can have dangerous interactions with alcohol. No medication should be assumed safe without checking - many can increase liver damage or sedation.
A
Correct answer
Explanation
Allergic rhinitis is indeed the proper medical terminology for what is commonly called 'hay fever' - an allergic inflammation of the nasal mucosa causing sneezing, itching, congestion, and runny nose. The term 'hay fever' is a misnomer as it doesn't involve fever and isn't caused by hay, but allergic rhinitis is the accurate clinical term.
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Histamines
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Histamine inhibitors
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Antihistamines
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Antimetabolites
C
Correct answer
Explanation
Antihistamines are the class of drugs that block histamine receptors and are used to treat allergic reactions. 'Histamines' are the inflammatory chemicals that cause allergy symptoms, 'histamine inhibitors' is not the standard terminology, and 'antimetabolites' are cancer/immune-suppressing drugs unrelated to allergy treatment. Antihistamines work by blocking the H1 histamine receptors to prevent allergic symptoms.
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Lead Silver Drug
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Lysergic acid Diethylamide
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Lysergic Silver Drug
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None
B
Correct answer
Explanation
LSD stands for Lysergic acid Diethylamide, a potent psychedelic drug. It was first synthesized in 1938 and became famous for its consciousness-altering effects. The name comes from its chemical structure based on lysergic acid.
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Antifluviral Medications
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Antiviral Medications
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Antifluval Medications
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PostViral Medications
B
Correct answer
Explanation
Medications used to treat viral infections like influenza are called antiviral medications. These drugs work by inhibiting virus replication. Options A and C are not standard medical terms.
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Wingardium Leviosa
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Petrificus Totalus
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Alohomora
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Impedimenta
B
Correct answer
Explanation
Petrificus Totalus is the Full Body-Bind Curse that Hermione used on Neville to stop him from preventing them from leaving Gryffindor Tower at night. Wingardium Leviosa is the levitating spell, Alohomora opens locks, and Impedimenta is the impediment jinx.
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Metavenine
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Zidovudine
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Navirapine
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Ritonavir
A
Correct answer
Explanation
Zidovudine, Nevirapine, and Ritonavir are all antiretroviral drugs used in HIV treatment. 'Metavenine' is not a recognized antiretroviral medication. The correct answer is A - Metavenine is not an antiretroviral drug.
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a pair of scissors
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retified spirit
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boric acid
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pain killing tablets like anacin
D
Correct answer
Explanation
Basic first aid kits contain bandages, antiseptics (like rectified spirit), scissors, and basic wound care supplies (like boric acid). Painkillers require proper medical assessment and dosage instructions, so they're not typically included in basic first aid boxes.
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A small allowance or wage
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Harmless substance prescribed as a dummy pill
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Central, critical
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Pacify, conciliate
B
Correct answer
Explanation
A placebo is a harmless substance or dummy treatment with no therapeutic effect, used in clinical trials as a control to compare against the actual treatment being tested. Option A describes 'pittance', option C describes 'pivotal', and option D describes 'appease'.