Chemistry · Biology

Pharmacology and Therapeutics

1,643 Questions

Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.

Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests

Pharmacology and Therapeutics Questions

Multiple choice

Indol-1 is popular for

  1. beta-blocker

  2. beta blocker and calcium channel blocker

  3. pH indicator

  4. calcium indicator

  5. both (1) and (2)

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

This option is correct because indol-1 is a popular calcium indicator similar to fura-2. In contrast to fura-2, indol-1 has a dual emission peak in Ca free solution in 475 nm while in the presence of Ca, the emission is shifted to 400 nm.

Multiple choice

ADME-TOX Prediction tool is

  1. ADME predictor

  2. ADME pr

  3. ADME cal

  4. None of these
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

ADME-TOX prediction tools help forecast Absorption, Distribution, Metabolism, Excretion, and Toxicity properties of drug candidates. 'ADME predictor' is the standard naming convention for such tools.

Multiple choice

Which of the following substances, if introduced into the blood stream, would cause coagulation of blood at the site of its introduction?

  1. Thromboplastin

  2. Fibrinogen

  3. Heparin

  4. Prothrombin
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

 Thromboplastin is a plasma protein aiding blood coagulation through catalyzing the conversion of prothrombin to thrombin. So, if introduced into the blood stream, it would cause coagulation of blood at the site of its introduction.

Multiple choice

Which among the following statements is/are correct?

A. Castor oil is obtained from Brassica rapa var. oleifera. B. Ephedra species produce the alkaloid ephedrine.
C. Topotecan is an anticancer agent extracted from Camptotheca sp.

  1. Only A

  2. Only B

  3. Only C

  4. Both A and B

  5. Both B and C
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

This option is correct because Ephedra species produce the alkaloid ephedrine, which is used in various medications and the cancer treatment drug topotecan is an extract of Camptotheca sp.

Multiple choice

Vasicine alkaloid, which is used as a bronchodilator in therapeutics, is obtained from the plant(s)

A. Adhatoda vasica B. Withania somniferum C. Astragalus gummifer

  1. Only A

  2. Only B

  3. Only C

  4. Both A and B

  5. Both B and C
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

The indigenous medicinal plant, Adhatoda vasica, commonly known as vasaka, is used as a herbal remedy for allergen-induced bronchial obstruction, asthma and tuberculosis. It contains Vasicine alkaloid.

Multiple choice

Which of the following pairs is not correctly matched?

  1. Pyrethrin : Chrysosporium indicum

  2. Digitalis : Digitalis purpurea

  3. Physostigmine : Physostigma venenosum

  4. Morphine : Papaver somniferum

  5. Pilocarpine : Pilocarpus sp.
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

The Pyrethrins are a pair of natural organic compounds, which are normally derived from Chrysanthemum cinerariifolium that have potent insecticidal activity. The alkaloid solanine is derived from unripe fruits of Solanum dulcamara and showed antidermatophytic activity against Chrysosporium indicum.

Multiple choice

Which of the following is a pair of synthetic estrogens?

  1. Estrone and Estriol

  2. Diethylstilbestrol and Fosfestrol

  3. Estriol and Fosfestrol

  4. Chlorotrianisene and Estrone

  5. Estrone and Fosfestrol
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Correct answer. Diethylstilbestrol is a synthetic nonsteroidal estrogen that was first synthesised in 1938. Fosfestrol is a synthetic estrogen used as an antineoplastic agent.