Which of the following drugs belonging to ansamycin family has received orphan drug status?
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Gelandamycin
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Rifaximin
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Rifampin
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Herbimycin
B
Correct answer
Explanation
Rifaximin is used to treat traveler's diarrhoea, irritable bowel syndrome and hepatic encephalopathy, for which it received orphan drug status from the U.S. Food and Drug Administration in 1998. An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition. Rifaximin has orphan drug status for the treatment of hepatic encephalopathy, which is a rare disease.