Biology
Human Immunity and Blood
2,096 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
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Test tube C
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Test tube D
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Test tube B
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Test tube A
D
Correct answer
Explanation
Blood is red in colour due to haemoglobin present in the red blood cells. Therefore, test tube A will show unusual colour of blood because of deficiency in red blood cells.
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Fibrinogen
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Heparin
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Thrombin
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Globin
B
Correct answer
Explanation
Heparin is a natural anticoagulant substance found in blood, produced by mast cells and basophils. It prevents blood clotting by inhibiting thrombin. Fibrinogen and thrombin are actually involved in blood clotting (coagulation), not preventing it. Globin is a protein component of hemoglobin and unrelated to clotting.
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decorin
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fibronectin
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integrins
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fibrin
D
Correct answer
Explanation
Fibrin is a fibrous protein involved in the clotting of blood and is non-globular. It is a fibrillar protein that is polymerised to form a mesh that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site.
D
Correct answer
Explanation
Blood group O lacks both A and B antigens on red blood cells. It is known as the 'universal donor' because the absence of antigens means it can be transfused to recipients with any blood type without causing an immune reaction.
A
Correct answer
Explanation
Agglutination is the clumping of cells, most commonly observed in blood typing when antibodies react with antigens on red blood cells. It is a fundamental immunological reaction used in blood compatibility testing.
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Alanine
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Asparagine
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Citrulline
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Creatine
A
Correct answer
Explanation
Alanine is necessary for the maintainance of proper blood glucose level from dietary protein. It stimulates lymphocyte production and may help people who have immune suppression. It also strengthens the immune system by producing antibodies.
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C1 to C9
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C1 to C5
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C1, C4, C2 and C3
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C5a
B
Correct answer
Explanation
Complements C1 to C5 are activated during endotoxin inactivation.
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They are fixed macrophages.
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They are wandering macrophages.
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They are found in the bones.
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They are killer cells.
B
Correct answer
Explanation
This is the correct option. Wandering macrophages are the macrophages that leave blood and migrate to an infected tissue. Peritoneal macrophages are wandering macrophages.
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Cytotoxic T-cells
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Regulatory T-cells
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Killer T-cells
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Memory T-cells
B
Correct answer
Explanation
Regulatory T-cells also known as suppressor and helper T-cells call in phagocytes to destroy bacterial cells.
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Polymorphonuclear granulocytes
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Lysosomal cells
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Monocytes
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Kuffer cells
C
Correct answer
Explanation
Monocytes are the precursors of macrophages. They differentiate into macrophages.
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histamines
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monokines
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lymphokines
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antibodies
D
Correct answer
Explanation
Antibodies are the regulatory proteins released by the activated T-cells.
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Regulatory T-cells
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Helper T-cells
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Killer T-cells
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γδ T-cells
C
Correct answer
Explanation
Killer T-cells recognise the antigens coupled to class I MHC molecules.
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Helper T-cells
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Memory T-cells
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Cytotoxic T-cells
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Suppressor T-cells
B
Correct answer
Explanation
Memory T-cells typically express the cell surface protein CD45RO. It is an essential regulator of T and B-cell antigen receptor signaling.
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Myelin sheath
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Small intestine
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Blood vessels
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Eyes
C
Correct answer
Explanation
Inflammation of blood vessels throughout the body, swelling, redness, heat and pain takes place in Behcet's syndrome.
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Normal number of B-cells with decreased IgG and IgA and increased IgM
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B-cells are present but with reduction in 2 or more isotypes
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Complete lack of antibodies
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Selective immunoglobulin A deficiency
C
Correct answer
Explanation
In X-linked agammaglobulinemia, B-cells are not generated. Due to this, antibodies are not formed and it manifests as a complete lack of antibodies in their bloodstream. It happens due to a mutation in X-chromosome.