Human Immunity and Blood

Uncontrolled proliferation of a cell type present in the blood and its precursors in the bone marrow is called leukaemia.

Rheumatoid arthritis is an autoimmune disorder.

Humoral immune system is formed by antibodies.

Mucus in the respiratory tract is a physical barrier of innate immunity.

Interferon is an antiviral protein which act as a cytokine barrier of innate immunity

Apart from B group, O can also be transfused as it is an universal donor and does not contain any antigens.

Thymus plays a major role in the development of the immune system.

Leukemia is a cancer of blood-forming tissues, primarily the bone marrow and lymphatic system. It involves the overproduction of abnormal white blood cells, which crowd out healthy blood cells and cannot function properly. While it can spread to other organs, it originates in and primarily affects the blood and blood-producing tissues.

 T  lymphocytes are a type of white blood cells involved in cell mediated immunity.

 Antibodies belong to immunoglobulins which are glycoproteins in blood plasma used in immunity and contain oligosacharride chains.

 Immature B cells which are never exposed to an antigen express only IgM antibody isotype  but express IgD too,when they are mature.

 IgE antibodies bind to allergens and trigger release of histamine from mast cells and thus gets involved in allergies.

 IgE isotype is found only in mammals and is involved in allergies.

 Presence of rhesus factor in a person's Rh blood group system is denoted by the presence of D antigen on red blood cells surface.

 Alloimmune condition refers to a condition when the body gains immunity from another individual of the same species. In erythroblastocis foetalis, some  maternal antibodies pass through placenta and attack red blood cells of the foetus causing anaemia and other life threatening symptoms in the newborn.