Multiple choice

The presence of which of the following is helpful in the diagnosis of ankylosing spondylitis [AS]?

  1. Serum antinuclear antibodies [ANAs]

  2. Rheumatoid factor in the serum

  3. HLA-B27

  4. Female gender

  5. HLA-B8
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The HLA-B27 test is primarily ordered to help strengthen or confirm a suspected diagnosis of ankylosing spondylitis (AS). Over 90% of affected individuals are HLA-B27 positive.

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