Multiple choice

Which of the following is not included in the serological findings in patients with systemic lupus erythematosus (SLE)?

  1. Raised serum IgG levels

  2. Antibodies to double-stranded DNA

  3. Decreased C3 and C4 levels

  4. A positive lupus anticoagulant

  5. Antibodies to cyclic citrullinated peptide (anti-CCP antibodies)
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Anti-CCP antibodies are found in >96% of patients with RA and not in other inflammatory conditions, making this assay specific for RA and therefore useful in clinical practice.

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