Multiple choice

Which complement factor is associated with C1q deficiency which occurs due to formation of C1q antibodies?

  1. Partial lipodystrophy

  2. Type II membranoproliferative glomerulonephritis (MPGN II)

  3. Hypocomplementemic urticarial vasculitis syndrome (HUVS)

  4. Systemic lupus erythematosus (SLE)

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Hypocomplementemic urticarial vasculitis syndrome (HUVS) (also called SLE-related syndrome or chronic hypocomplementemic cutaneous vasculitis) is a disorder associated with anti-C1q antibodies that leads to classical pathway activation and chronic decreases in C1, C2, C4 and C3 levels.