Multiple choice

The activation of the complement components occurs via three distinct pathways. Which of the following component (s) is specific to the ‘Alternate Pathway’?

  1. Factor B and D

  2. Mannose binding protein

  3. Clqr2s2

  4. C2
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A Correct answer
Explanation

The alternative pathway of the complement system is activated by direct contact with pathogen surfaces and involves Factors B and D, whereas the classical pathway involves C1 (C1q, C1r, C1s) and the lectin pathway involves mannose-binding protein.

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