Multiple choice

Systemic lupus erythematosus is a chronic and often disabling autoimmune disease. Which of the following might be helpful in cerebral systemic lupus erythematosus (SLE)?

  1. Antinuclear antibodies

  2. Antineuronal antibodies

  3. C8 levels in serum

  4. C3 levels in CSF

  5. Immune complex levels in CSF
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A Correct answer
Explanation

A marker of SLE, but also found in many other diseases; their presence in a patient suspected of having cerebral lupus indicates that dsDNA binding antibodies and ENA antibodies must be measured. These will be present in SLE, including cerebral SLE.

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