Biology
Human Immunity and Blood
2,096 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
What are the two main subsets of CD4+ Helper T cells?
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Th1 and Th2 cells
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Th1 and Th17 cells
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Th2 and Th17 cells
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Th1, Th2, and Th17 cells
A
Correct answer
Explanation
CD4+ Helper T cells can be divided into two main subsets: Th1 cells and Th2 cells. Th1 cells are involved in cell-mediated immunity, while Th2 cells are involved in humoral immunity.
What is the role of Th1 cells in the immune response?
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Producing antibodies
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Killing infected cells
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Activating macrophages
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Suppressing immune responses
C
Correct answer
Explanation
Th1 cells play a crucial role in cell-mediated immunity by releasing cytokines that activate macrophages and other phagocytic cells, enhancing their ability to kill intracellular pathogens.
What is the role of Th2 cells in the immune response?
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Killing infected cells
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Producing antibodies
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Activating macrophages
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Suppressing immune responses
B
Correct answer
Explanation
Th2 cells play a critical role in humoral immunity by releasing cytokines that stimulate B cells to differentiate into antibody-producing plasma cells, leading to the production of antibodies against pathogens.
What is the role of Th17 cells in the immune response?
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Producing antibodies
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Killing infected cells
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Activating macrophages
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Promoting inflammation
D
Correct answer
Explanation
Th17 cells are involved in promoting inflammation and immune responses against extracellular bacteria and fungi. They release cytokines that recruit neutrophils and other inflammatory cells to the site of infection.
What is the process by which T cells differentiate into effector T cells?
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Activation
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Proliferation
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Differentiation
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All of the above
D
Correct answer
Explanation
T cell differentiation into effector T cells involves a series of steps, including activation, proliferation, and differentiation into specific effector T cell subsets, such as cytotoxic T cells, helper T cells, and regulatory T cells.
What are the different types of effector T cells?
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Cytotoxic T cells (Tc cells)
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Helper T cells (Th cells)
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Regulatory T cells (Treg cells)
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Memory T cells
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All of the above
E
Correct answer
Explanation
Effector T cells include cytotoxic T cells (Tc cells), helper T cells (Th cells), regulatory T cells (Treg cells), and memory T cells. Each subset has a distinct role in the immune response.
What is the role of cytokines in T cell activation and differentiation?
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Activating T cells
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Promoting proliferation
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Inducing differentiation
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All of the above
D
Correct answer
Explanation
Cytokines play a crucial role in T cell activation, proliferation, and differentiation. They are produced by various immune cells and act as signaling molecules that regulate T cell responses.
Which signaling pathway is commonly associated with rapid cellular responses?
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cAMP signaling pathway
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MAP kinase signaling pathway
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JAK-STAT signaling pathway
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TGF-beta signaling pathway
A
Correct answer
Explanation
The cAMP signaling pathway is known for its rapid activation and involvement in various cellular processes.
Which signaling pathway is commonly associated with long-term cellular responses?
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cAMP signaling pathway
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MAP kinase signaling pathway
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JAK-STAT signaling pathway
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TGF-beta signaling pathway
D
Correct answer
Explanation
The TGF-beta signaling pathway is known for its involvement in long-term cellular responses, including cell growth, differentiation, and apoptosis.
Which type of stem cell is commonly used in cord blood banking?
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Embryonic stem cells
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Induced pluripotent stem cells
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Adult stem cells
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Hematopoietic stem cells
D
Correct answer
Explanation
Hematopoietic stem cells, found in cord blood, are commonly collected and stored in cord blood banks for potential use in treating blood-related diseases.
What is the most common type of Sickle Cell Anemia?
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HbSS
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HbSC
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HbSβ-thalassemia
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HbSE
A
Correct answer
Explanation
HbSS is the most common type of Sickle Cell Anemia, characterized by the presence of two copies of the sickle cell gene (βS).
Which of the following is a type of cancer that originates in the cells of the blood-forming tissues?
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Lung cancer
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Breast cancer
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Leukemia
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Colon cancer
C
Correct answer
Explanation
Leukemia is a type of cancer that originates in the cells of the blood-forming tissues, such as the bone marrow and lymph nodes.
Which of the following is NOT a type of cell adhesion molecule?
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Cadherins
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Integrins
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Selectins
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Immunoglobulins
D
Correct answer
Explanation
Immunoglobulins are not a type of cell adhesion molecule, but rather a type of antibody.
Which of the following is a type of cell that is responsible for the formation of new blood cells?
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Hematopoietic Stem Cells
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Neural Stem Cells
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Mesenchymal Stem Cells
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Adipose Stem Cells
A
Correct answer
Explanation
Hematopoietic stem cells are a type of cell that is responsible for the formation of new blood cells.
What is the sacrament in which a person receives the body and blood of Christ?
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Baptism
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Confirmation
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Eucharist
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Penance
C
Correct answer
Explanation
The Eucharist is the sacrament in which a person receives the body and blood of Christ.