Biology
Endocrine and Metabolic Disorders
617 Questions
Endocrine and metabolic disorders focus on diseases caused by hormonal imbalances, such as goitre, diabetes mellitus, and hyperthyroidism. Test takers will find questions related to disease causes, diagnostic tests like Cushing's syndrome indicators, and clinical treatments. This is a crucial biology topic frequently asked in medical entrance and public service commission examinations.
Thyroid gland disordersGoitre causesDiabetes mellitus characteristicsHyperthyroidism treatmentsGrowth hormone deficiency
Endocrine and Metabolic Disorders Questions
Which one of the following hormone has potential to prevent certain chronic disease like cancer and multiple sclerosis?
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Melatonin
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Testosterone
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Estrogen
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Dehydro-epiandro sterone
D
Correct answer
Explanation
Dehydroepiandrosterone (DHEA) is an important endogenous steroid hormone. It is the most abundant circulating steroid hormone in humans. DHEA is used to treat systemic lupus erythematosus (SLE), osteoporosis, multiple sclerosis (MS), low levels of steroid hormones (Addison disease), depression, schizophrenia, chronic fatigue syndrome (CFS), and to slow the progression of Parkinson disease. It is also used for preventing heart disease, breast cancer, diabetes, and metabolic syndrome. DHEA is used for weight loss, for decreasing the symptoms of menopause, and for boosting the immune system. It is naturally produced in the human body.
So, the correct answer is option D.
What is the term for a group of metabolic disorders characterized by high blood sugar levels?
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Diabetes mellitus
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Hypertension
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Dyslipidemia
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Obesity
A
Correct answer
Explanation
Diabetes mellitus is a group of metabolic disorders characterized by high blood sugar levels due to the body's inability to produce or effectively use insulin.
What is the primary mechanism of action of insulin?
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Inhibits gluconeogenesis
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Stimulates glycogen synthesis
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Increases glucose uptake by cells
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All of the above
D
Correct answer
Explanation
Insulin has multiple mechanisms of action, including inhibiting gluconeogenesis, stimulating glycogen synthesis, and increasing glucose uptake by cells.
Which of the following is a common adverse effect of thiazolidinediones?
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Hypoglycemia
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Weight gain
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Edema
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Lactic acidosis
B
Correct answer
Explanation
Weight gain is a common adverse effect of thiazolidinediones, which are a class of antidiabetic drugs.
What is the primary mechanism of action of levothyroxine?
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Inhibits thyroid peroxidase
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Increases thyroid hormone production
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Decreases thyroid hormone production
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None of the above
B
Correct answer
Explanation
Levothyroxine is a synthetic thyroid hormone that increases thyroid hormone production.
Which of the following is a common adverse effect of glucocorticoids?
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Cushing's syndrome
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Hyperglycemia
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Immunosuppression
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All of the above
D
Correct answer
Explanation
Glucocorticoids can cause a variety of adverse effects, including Cushing's syndrome, hyperglycemia, and immunosuppression.
What is the primary mechanism of action of antithyroid drugs?
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Inhibits thyroid peroxidase
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Increases thyroid hormone production
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Decreases thyroid hormone production
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None of the above
A
Correct answer
Explanation
Antithyroid drugs inhibit thyroid peroxidase, an enzyme involved in thyroid hormone production.
Which of the following is a common adverse effect of androgen therapy?
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Acne
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Hirsutism
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Deepening of the voice
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All of the above
D
Correct answer
Explanation
Androgen therapy can cause a variety of adverse effects, including acne, hirsutism, and deepening of the voice.
Which of the following is a risk of parathyroidectomy?
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Hypoparathyroidism
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Hyperparathyroidism
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Thyroid storm
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Adrenal insufficiency
A
Correct answer
Explanation
Hypoparathyroidism is a condition in which the parathyroid glands do not produce enough parathyroid hormone (PTH). This can lead to low blood calcium levels and a variety of symptoms, including muscle cramps, tingling sensations, and seizures.
Which of the following is a complication of adrenal surgery?
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Adrenal insufficiency
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Hypertension
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Diabetes mellitus
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Obesity
A
Correct answer
Explanation
Adrenal insufficiency is a condition in which the adrenal glands do not produce enough hormones, such as cortisol and aldosterone. This can lead to a variety of symptoms, including fatigue, weight loss, and low blood pressure.
What is the most common type of endocrine surgery performed on children?
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Thyroidectomy
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Parathyroidectomy
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Adrenalectomy
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Pituitary surgery
A
Correct answer
Explanation
Thyroidectomy is the most common type of endocrine surgery performed on children. It is typically performed to treat thyroid cancer or Graves' disease.
Which of the following is a risk of pituitary surgery?
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Diabetes insipidus
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Adrenal insufficiency
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Hypothyroidism
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All of the above
D
Correct answer
Explanation
Pituitary surgery can damage the pituitary gland and lead to a variety of hormonal deficiencies, including diabetes insipidus, adrenal insufficiency, and hypothyroidism.
What is the most common type of endocrine surgery performed on the elderly?
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Thyroidectomy
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Parathyroidectomy
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Adrenalectomy
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Pituitary surgery
A
Correct answer
Explanation
Thyroidectomy is the most common type of endocrine surgery performed on the elderly. It is typically performed to treat thyroid cancer or Graves' disease.
Which of the following is a risk of endocrine surgery?
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Infection
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Bleeding
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Nerve damage
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All of the above
D
Correct answer
Explanation
Endocrine surgery can be associated with a variety of risks, including infection, bleeding, and nerve damage.
Which of the following is a type of endocrine surgery that is performed on patients with Cushing's syndrome?
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Thyroidectomy
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Parathyroidectomy
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Adrenalectomy
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Pituitary surgery
C
Correct answer
Explanation
Adrenalectomy is a type of endocrine surgery that is performed on patients with Cushing's syndrome. It is used to remove the adrenal glands, which produce the hormone cortisol.