Biology · General Awareness
Viral Diseases and Immunity
807 Questions
Viral diseases and immunity cover the structure, transmission, and diagnosis of viruses like HIV. Questions focus on disease pathways, immune responses, and prevention. Strong knowledge here provides an edge in biology scoring.
HIV and AIDS structureVirus transmission methodsImmune system deficiencyPathogen risk groupsMedical diagnosis methods
Viral Diseases and Immunity Questions
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Herpes zoster
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HIV-2
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Vesicular stomatitis virus
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Proteus mirabilis
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Epstein-Barr virus
E
Correct answer
Explanation
Epstein-Barr virus is associated with Burkitt's lymphoma and with naso-pharyngeal carcinoma.
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EBV herpes virus
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An increased incidence in gliomas.
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CNS lymphoma
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Paraproteinemia
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An increased incidence of thrombocytopenia.
B
Correct answer
Explanation
A glioma is a type of tumor that starts in the brain or spine. It is called a glioma because it arises from glial cells. An increased incidence in gliomas has no association with HIV infection.
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ELISA
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Dot blot assays
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Western blot
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Viral isolation
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Polymerase chain reaction (PCR)
E
Correct answer
Explanation
In case of HIV infection this test finds either the RNA of the HIV virus or the HIV DNA in white blood cells infected with the virus. The PCR test is very useful to find a very recent infection.
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The acquired immune deficiency syndrome (AIDS).
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Complete DiGeorge syndrome
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Purine nucleoside phosphorylase (PNP) deficiency
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Severe protein-calorie malnutrition
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Wiskott-Aldrich syndrome
B
Correct answer
Explanation
In complete DiGeorge syndrome there is a total failure of the thymus to develop and thus neither CD4-positive T-cells nor CD8-positive T-cells are formed. Note, however, that most cases of DiGeorge syndrome are 'partial' with some thymic development and thus not a complete absence of T-cells.
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An increased incidence of thrombocytopenia.
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An increased incidence in gliomas.
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Paraproteinemia
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CNS lymphoma
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EBV herpes virus
B
Correct answer
Explanation
A glioma is a type of tumor that starts in the brain or spine. It is called a glioma because it arises from glial cells. An increased incidence in gliomas has no association with HIV infection.
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bacterial; immune system
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viral; blood
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bacterial; blood
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viral; liver
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viral; immune system
A
Correct answer
Explanation
In case of AIDS, the virus affects the immune system, damages its functions and leads to death.
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AIDS can spread through sexual contact and through infected blood as well.
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Malarial protozoans enter the body through mosquito bite and infect the brain.
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Viruses are submicroscopic organisms.
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Acute and chronic diseases have different effects on our health.
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AIDS infects the immune system of the body.
B
Correct answer
Explanation
Malarial protozoans enter the body through mosquito bite and travel to the liver and the RBCs.
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dsDNA virus
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ssDNA virus
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ssRNA virus
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dsRNA virus
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activator B cells.
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T4 lymphocytes.
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cytotoxic T cells.
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all lymphocytes.
B
Correct answer
Explanation
HIV infection is associated with the progressive loss of CD4(+) T cells through their destruction or decreased production.
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Leukemia
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Herpes
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HIV
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Syphilis
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Rabies
E
Correct answer
Explanation
Rabies is a viral disease that causes acute encephalitis in warm blooded animals. Negri bodies are eosinophilic sharply outlined pathognomonic inclusion bodies found in the cytoplasm of certain nerve cells containing the virus of rabies especially in Ammon's horn of the hippocampus. It is also found in the cerebellar cortex of postmortem brain samples of rabies victims. They consist ribonuclear proteins produced by the virus.
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Chronic carrier
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Active carrier
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Healthy carrier
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Incubatory carrier
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Convalescent carrier
E
Correct answer
Explanation
Convalescent carrier is a person who has recovered from the symptoms of an infectious disease but is still capable of transmitting pathogens to others. Persons in this category are the most frequent source of infection for others.
E
Correct answer
Explanation
HIV-1 virus is made up of protein envelope and two copies of single stranded RNA of the genome. The envelope contains 72 external spikes. This spike is made up from the glycoproteins GP120 and GP41. Here GP stands for glycoprotein and the number refers the mass of protein. GP120 is present in external spike and GP41 is in transmembrane.
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CD19
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CD4
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CD40 ligand
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CD8
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CD25
B
Correct answer
Explanation
This is a major portal of entry, though not the only one.
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mottling
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necrosis
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ring spots
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stunts
B
Correct answer
Explanation
Necrosis is a form of cell injury, which results in the premature death of cells in the living tissue.
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picornavirus
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JC virus
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hepatitis A
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dependovirus
B
Correct answer
Explanation
Progressive Multifocal Leukoencephalopathy, a common complication of AIDS, is caused by JC virus. This virus gets activated in immunosupressed condition and lead to paralysis and death.