Biology

Human Immunity and Blood

2,096 Questions

Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.

Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology

Human Immunity and Blood Questions

Multiple choice
  1. Bone marrow

  2. Brain

  3. Lymph node

  4. Blood cells

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Leukemia is a cancer of blood-forming tissues, primarily originating in bone marrow where abnormal white blood cells are produced. While it affects blood cells, the root cause and primary site is bone marrow dysfunction.

Multiple choice
  1. A

  2. B

  3. O

  4. AB

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

AB blood group is the universal recipient because it has both A and B antigens on red blood cells but no anti-A or anti-B antibodies in plasma. This allows AB individuals to receive blood from any ABO group (A, B, AB, or O) without antibody-mediated rejection. Types A, B, and O can only receive from their own type or O (universal donor).

Multiple choice
  1. NK cells have rearranged T-cell receptor genes.

  2. NK cells are unaffected by IFN alpha.

  3. NK cells are more active against targets with upregulated MHC class I.

  4. NK cells can kill certain virally-infected cells.

  5. NK cells can kill all virally-infected cells.

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Like cytotoxic T-cells, NK cells can inhibit viral replication by killing the host cell. The difference is that cytotoxic T-cells have a receptor for a specific T-cell epitope whereas NK cells have a broader specificity.

Multiple choice
  1. Development of B and T lymphocytes

  2. Attraction of lymphocytes to infected site

  3. Chemoattractant

  4. Inflammation

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

sPLA2 (Secreted phospholipases A2) have been shown to promote inflammation in mammals by catalysing the first step of the arachidonic acid pathway by breaking down phospholipids.

Multiple choice
  1. R.B.C.

  2. Lymphocytes

  3. Monocytes

  4. Platelets

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Platelets (thrombocytes) are the blood components responsible for clotting - they gather at wound sites, release clotting factors, and form platelet plugs. RBCs carry oxygen, lymphocytes are white blood cells for immunity, and monocytes are also white blood cells that fight infection but don't directly clot blood.

Multiple choice
  1. only group B

  2. only group AB

  3. only group A

  4. any blood group

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

The correct answer is 'any blood group' because persons with blood group AB are called 'universal recipients' - they have both A and B antigens on their red blood cells and no anti-A or anti-B antibodies. This means they can safely receive blood from any blood group (A, B, AB, or O) without having a transfusion reaction.

Multiple choice
  1. Red blood cells

  2. Plasma

  3. White blood cells

  4. Hemoglobin

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The correct answer is white blood cells (leukocytes), which are the cells in the human body that fight infection. They are part of the immune system. Red blood cells carry oxygen, plasma is the fluid component, and hemoglobin is the oxygen-carrying protein in red blood cells.