Biology
Human Immunity and Blood
2,096 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
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red blood cells
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liquid residue
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lymph
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platelets
C
Correct answer
Explanation
Lymph is the clear-to-yellowish fluid in intercellular spaces and lymphatic vessels. It's derived from interstitial fluid and contains white blood cells, similar to blood plasma.
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RBC
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WBC
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Blood platelets
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Lymph
C
Correct answer
Explanation
Blood platelets (thrombocytes) are cell fragments that are essential for blood clotting. They clump together at the site of injury and release clotting factors. RBCs carry oxygen, WBCs fight infection, and lymph is part of the lymphatic system - none directly cause clotting.
D
Correct answer
Explanation
Blood type O negative is the universal donor because it lacks A, B, and Rh antigens on red blood cells. This means it won't trigger an immune response in recipients with any blood type. Type A, B, and AB all have antigens that would react with incompatible recipients.
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RBCs
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WBCs
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Plasanta
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Plasma
C
Correct answer
Explanation
Blood consists of RBCs, WBCs, platelets, and plasma. 'Plasanta' is not a real blood component - it appears to be a typo, likely intended to be 'placenta' (which is an organ during pregnancy, not in blood) or it's a nonsense word. Either way, it's correctly identified as not being present in blood.
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OKT3: T3
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OKT4: T4
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OKT6: T6
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OKT11: T11
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J5: B-cells
A
Correct answer
Explanation
Monoclonal antibody OKT3 has antigen of type T3, which represents reactivity with epidermal Langerhan’s cells.
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cytokines
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thrombin
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histamine
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sugar moieties
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Both (1) and (2)
D
Correct answer
Explanation
Selectins bind to sugar moieties and are considered to be a type of lectin.
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P and Q
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P and R
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Q and R
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Q and S
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R and S
E
Correct answer
Explanation
The gene for factor VIII is located on the X chromosome.
Factor VIII is produced in liver sinusoidal cells and endothelial cells outside of the liver throughout the body.
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IgA and IgD
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IgE and IgG
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IgG and IgM
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IgM and IgW
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IgW and IgY
E
Correct answer
Explanation
IgW and IgY are not found in mammals.
IgWs are found in birds and reptiles.
IgYs found in sharks and skates.
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Neutrophils
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Eosinophils
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Basophils
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Lymphocytes
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Monocytes
D
Correct answer
Explanation
Lymphocytes are the second most common white blood cells (20 - 45% of all leukocytes).
Match Column – I (type of lymphocyte) with Column – II (function) and select the correct option.
| |
|
| Column – I |
|
|
Column – II |
| P. NK cells |
1. Lysis of virally infected cells and tumour cells |
| Q. Helper T cells |
2. Secretion of antibodies |
| R. B cells |
3. Release of cytokines and growth factors that regulate other immune cells |
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P - 1, Q - 2, R - 3
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P - 1, Q - 3, R - 2
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P - 3, Q - 1, R - 2
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P - 3, Q - 2, R - 1
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P - 2, Q - 3, R - 1
B
Correct answer
Explanation
Natural Killer Cells (or NK cells) are a type of cytotoxic lymphocyte critical to the innate immune system. NK cells provide rapid responses to virally infected cells and respond to tumor formation.
Helper T cells help the activity of other immune cells by releasing T cell cytokines. They are essential in B cell antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages.
The principal functions of B cells are to make antibodies against antigens.
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1, 2 and 3
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2 and 3
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2, 4 and 5
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4 and 5
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4, 5 and 6
D
Correct answer
Explanation
Lymphocytes and monocytes are types of agranular leukocytes.
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Fibrinogen
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Heparin
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Thrombin
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Globin
B
Correct answer
Explanation
Heparin is a naturally occurring anticoagulant produced by mast cells and basophils. It prevents blood clot formation by enhancing the activity of antithrombin III, which inhibits thrombin and other clotting factors. Fibrinogen and thrombin are actually pro-coagulant substances involved in clot formation, while globin is a protein component of hemoglobin.
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heart
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liver
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spleen
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pancreas
B
Correct answer
Explanation
Kupffer cells are resident macrophages lining liver sinusoids, phagocytosing pathogens, damaged cells, and debris from blood passing through the liver. They're not found in heart, spleen (which has different macrophage types), or pancreas.
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aphthous ulcer
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sickle cell anemia
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iron deficiency anemia
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pemphigus
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all of the above
D
Correct answer
Explanation
This is the correct answer because anitschkow cells are not found in pemphigus.
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Infectious mononucleosis
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Pemphigus
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Pleomorphic adenoma
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Thalassemia
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Aphthous ulcer
A
Correct answer
Explanation
Downey cells are seen in infectious mononucleosis.