Biology

Human Immunity and Blood

2,096 Questions

Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.

Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology

Human Immunity and Blood Questions

Multiple choice
  1. RBC

  2. WBC

  3. Blood platelets

  4. Lymph

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Blood platelets (thrombocytes) are cell fragments that are essential for blood clotting. They clump together at the site of injury and release clotting factors. RBCs carry oxygen, WBCs fight infection, and lymph is part of the lymphatic system - none directly cause clotting.

Multiple choice
  1. A

  2. B

  3. AB

  4. O

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Blood type O negative is the universal donor because it lacks A, B, and Rh antigens on red blood cells. This means it won't trigger an immune response in recipients with any blood type. Type A, B, and AB all have antigens that would react with incompatible recipients.

Multiple choice
  1. RBCs

  2. WBCs

  3. Plasanta

  4. Plasma

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Blood consists of RBCs, WBCs, platelets, and plasma. 'Plasanta' is not a real blood component - it appears to be a typo, likely intended to be 'placenta' (which is an organ during pregnancy, not in blood) or it's a nonsense word. Either way, it's correctly identified as not being present in blood.

Multiple choice
  1. cytokines

  2. thrombin

  3. histamine

  4. sugar moieties

  5. Both (1) and (2)

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Selectins bind to sugar moieties and are considered to be a type of lectin.

Multiple choice
  1. P and Q

  2. P and R

  3. Q and R

  4. Q and S

  5. R and S

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

The gene for factor VIII is located on the X chromosome. Factor VIII is produced in liver sinusoidal cells and endothelial cells outside of the liver throughout the body.

Multiple choice
  1. P - 1, Q - 2, R - 3

  2. P - 1, Q - 3, R - 2

  3. P - 3, Q - 1, R - 2

  4. P - 3, Q - 2, R - 1

  5. P - 2, Q - 3, R - 1

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Natural Killer Cells (or NK cells) are a type of cytotoxic lymphocyte critical to the innate immune system. NK cells provide rapid responses to virally infected cells and respond to tumor formation. Helper T cells help the activity of other immune cells by releasing T cell cytokines. They are essential in B cell antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages. The principal functions of B cells are to make antibodies against antigens.

Multiple choice
  1. Fibrinogen

  2. Heparin

  3. Thrombin

  4. Globin

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Heparin is a naturally occurring anticoagulant produced by mast cells and basophils. It prevents blood clot formation by enhancing the activity of antithrombin III, which inhibits thrombin and other clotting factors. Fibrinogen and thrombin are actually pro-coagulant substances involved in clot formation, while globin is a protein component of hemoglobin.

Multiple choice
  1. heart

  2. liver

  3. spleen

  4. pancreas

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Kupffer cells are resident macrophages lining liver sinusoids, phagocytosing pathogens, damaged cells, and debris from blood passing through the liver. They're not found in heart, spleen (which has different macrophage types), or pancreas.

Multiple choice
  1. aphthous ulcer

  2. sickle cell anemia

  3. iron deficiency anemia

  4. pemphigus

  5. all of the above

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

This is the correct answer because anitschkow cells are not found in pemphigus.