Multiple choice

Which of the following statements are false?

  1. Heat inactivation of serum is done to inactivate prions.
  2. Nude mice refer to transgenic mice.
  3. A humanised antibody is one in which the CDRs are from mouse, and the rest is from human.
  4. B-lymphocytes originate from the bone marrow.

  1. Only 1 and 2

  2. Only 1 and 3

  3. Only 2 and 3

  4. Only 2 and 4

  5. Only 3 and 4
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Yes, this is the correct answer. Both are false statements. Heat-inactivation of serum is done by heating to 56°C for 30 minutes to inactivate complement (a group of proteins present in sera that are part of the immune response). A nude mouse is a laboratory mouse from a strain with a genetic mutation causing deteriorated or absent thymus. This type of genetic mutation results in an inhibited immune system due to a greatly reduced number of T cells.

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