Human Immunity and Blood

IgG and IgM activate complement.

The half life of IgE immunoglobulins increases to 2 weeks if IgE molecules bind to mast cells.

The spleen where plasmablasts responsible for antibody production reside is the major site of specific IgM production.

The Fc region of antibody which gives the ability to an antibody to communicate with the other components of the immune system contains conserved glycosylation site.

The part of antibody which recognises an antigen is called paratope. It is a small portion of variable region of antibody that contains both heavy and light chains

IgG+ isotype is expressed on the surface of immature B-cells.

This option is correct.

Selectins are a family of molecules, not cells. l-selectin is involved in the entry of lymphocytes into lymph nodes and is the lymphocyte homing receptor, which recognises the high endothelial venule (HEV) addressin molecule.

There are receptors for C3b on the surface of phagocytic cells.

These are of the myeloid lineage.

By far, the vast majority of gamma delta T-cells are 'double negative' CD4–CD8–.

Plasma cells produce immunoglobulins of all isotypes, including IgE.

They are circulating immature macrophages or dendritic cells.

IL-8 produced by endothelial cells later in the inflammatory response is a powerful chemotactic agent for neutrophils.

64% of ALL are the pre-B-cell type.