Biology
Human Immunity and Blood
2,051 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
What is the primary target of the immune system in type 1 diabetes?
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Pancreatic beta cells
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Insulin receptors
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Glucose transporters
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Liver cells
A
Correct answer
Explanation
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys pancreatic beta cells, leading to a deficiency of insulin and an inability to regulate blood sugar levels.
Which of the following is a potential side effect of corticosteroids in the treatment of RDS?
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Hyperglycemia
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Gastrointestinal bleeding
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Increased risk of infection
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All of the above
D
Correct answer
Explanation
Hyperglycemia, gastrointestinal bleeding, and increased risk of infection are all potential side effects of corticosteroids in the treatment of RDS.
Which antibody is responsible for activating complement proteins, leading to the destruction of pathogens?
A
Correct answer
Explanation
IgM antibodies are able to activate complement proteins, which are a group of proteins that work together to destroy pathogens.
What is the role of IgD antibodies in the immune system?
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To activate B cells
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To neutralize toxins
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To provide long-term immunity
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To prevent allergies
A
Correct answer
Explanation
IgD antibodies are found on the surface of B cells and help to activate B cells when they encounter an antigen.
What is the role of antibodies in autoimmune diseases?
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Antibodies attack the body's own tissues
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Antibodies neutralize toxins
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Antibodies activate complement proteins
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Antibodies provide long-term immunity
A
Correct answer
Explanation
In autoimmune diseases, the immune system produces antibodies that attack the body's own tissues. This can lead to inflammation and damage to various organs and tissues.
What is the role of antibodies in antibody-dependent cell-mediated cytotoxicity (ADCC)?
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Antibodies bind to target cells and activate natural killer cells to kill the target cells
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Antibodies neutralize toxins
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Antibodies activate complement proteins
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Antibodies provide long-term immunity
A
Correct answer
Explanation
In antibody-dependent cell-mediated cytotoxicity (ADCC), antibodies bind to target cells and activate natural killer cells to kill the target cells. This is an important mechanism for the immune system to eliminate infected cells and cancer cells.
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Proteins produced by B cells
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Cells that engulf and destroy pathogens
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Chemicals that signal other immune cells
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Structures that filter out pathogens from the blood
A
Correct answer
Explanation
Antibodies are proteins produced by B cells that recognize and bind to specific antigens on pathogens, marking them for destruction.
What is the role of the bone marrow in the immune system?
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To produce antibodies
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To engulf and destroy pathogens
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To produce immune cells
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To filter out pathogens from the blood
C
Correct answer
Explanation
The bone marrow is responsible for producing immune cells, including B cells, T cells, and macrophages, which play crucial roles in the immune response.
Which type of immunodeficiency disorder is caused by a deficiency in the production or function of antibodies?
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Combined immunodeficiency
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Humoral immunodeficiency
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Cellular immunodeficiency
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Phagocytic immunodeficiency
B
Correct answer
Explanation
Humoral immunodeficiency is characterized by a deficiency in the production or function of antibodies, which are proteins that recognize and neutralize foreign substances in the body.
What is the most common type of primary immunodeficiency disorder?
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Severe combined immunodeficiency (SCID)
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Common variable immunodeficiency (CVID)
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X-linked agammaglobulinemia (XLA)
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Wiskott-Aldrich syndrome (WAS)
B
Correct answer
Explanation
Common variable immunodeficiency (CVID) is the most prevalent primary immunodeficiency disorder, characterized by a deficiency in the production of antibodies, leading to recurrent infections.
Which type of immunodeficiency disorder is characterized by a deficiency in the number or function of phagocytic cells, such as neutrophils and macrophages?
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Combined immunodeficiency
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Humoral immunodeficiency
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Cellular immunodeficiency
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Phagocytic immunodeficiency
D
Correct answer
Explanation
Phagocytic immunodeficiency is characterized by a deficiency in the number or function of phagocytic cells, which are responsible for engulfing and destroying foreign particles and microorganisms.
Which type of immunodeficiency disorder is characterized by a deficiency in the production or function of T cells?
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Combined immunodeficiency
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Humoral immunodeficiency
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Cellular immunodeficiency
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Phagocytic immunodeficiency
C
Correct answer
Explanation
Cellular immunodeficiency is characterized by a deficiency in the production or function of T cells, which play a crucial role in cell-mediated immunity and the recognition and destruction of infected cells.
Which diagnostic test is commonly used to measure the levels of antibodies in the blood?
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Complete blood count (CBC)
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Antibody titer test
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T cell count
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Chest X-ray
B
Correct answer
Explanation
Antibody titer tests are used to measure the levels of antibodies in the blood, which can help diagnose humoral immunodeficiency disorders.
Which type of immunodeficiency disorder is characterized by a deficiency in the production or function of natural killer (NK) cells?
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Combined immunodeficiency
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Humoral immunodeficiency
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Cellular immunodeficiency
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NK cell deficiency
D
Correct answer
Explanation
NK cell deficiency is characterized by a deficiency in the production or function of natural killer (NK) cells, which play a role in innate immunity and the recognition and destruction of infected cells.
Which type of immunodeficiency disorder is characterized by a deficiency in the production or function of complement proteins?
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Combined immunodeficiency
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Humoral immunodeficiency
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Cellular immunodeficiency
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Complement deficiency
D
Correct answer
Explanation
Complement deficiency is characterized by a deficiency in the production or function of complement proteins, which play a role in the activation of the immune system and the destruction of foreign particles.