The heart rate is increased by
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An increase in the activity of the sympathetic nerves that supply the heart
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A decrease in the activity of the parasympathetic (vagus) system
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An increase in the level of adrenalin in the circulation
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All of the above
A special neural centre in the medulla oblangata can moderate the cardiac function through autonomic nervous system (ANS). Neural signals through the sympathetic nerves (part of ANS) can increase the rate of heart beat, the strength of ventricular contraction and thereby the cardiac output. On the other hand, parasympathetic neural signals (another component of ANS) decrease the rate of heart beat, speed of conduction of action potential and thereby the cardiac output. Adrenal medullary hormones (adrenaline, noradrenaline) can also increase the cardiac output.