Tag: immunity and blood groups

Questions Related to immunity and blood groups

Erythroblastosis foetalis is caused when fertilisation takes place between gametes of

  1. $Rh^-$ female and $Rh^+$ male.

  2. $Rh^+$ female and $Rh^-$ male.

  3. $Rh^+$ female and $Rh^+$ male.

  4. $Rh^-$ female and $Rh^-$ male.


Correct Option: A
Explanation:
 Erythroblastosis foetalis is caused by transplacental transmission of maternal antibodies to foetal RBCs when  mother is Rh- and the foetus is Rh+.
So, the correct option is 'Rh- female and Rh+ male'

Consider the following statements about phagocytes in man. 
1) They provide the second line of defense. 
2) They can recognize and distinguish between self and non-self. 
3) They have antigen receptor.
Which of the above statements are true?

  1. Only 1 and 2

  2. Only 1 and 3

  3. Only 2 and 3

  4. All are true


Correct Option: B
Explanation:

Phagocytes are the type of cells present inside the body capable of engulfing bacteria and other small cells in the body and provide second line defense. It means that they destroy invaders in a generalized way and activate via antigen receptors that bind to an antibody attached to antigen without recognizing between self and non-self.

So the correct option is "Only 1 and 3".

Note the following :
(A) Skin                               (B) Phagocytes
(C) Antibodies                     (D) Inflammation 
(E) Antibodies                     (F) T- cells
(G) Fever                            (H) Antimicrobial proteins
(I) NK-cells                          (J) Secretions 
Identify the factors involved in $2^{nd}$ line of defence

  1. (B), (D), (G) and (I)

  2. (B), (C), (E) and (I)

  3. (D), (F), (H) and (J)

  4. (C), (E), (G) and (H)


Correct Option: A

Who is called the father of immunology?

  1. Louis Pasteur

  2. Robert Koch

  3. Edward Jenner

  4. Iwanowsky


Correct Option: C
Explanation:

  • Edward Jenner, an English physician, and scientist is called the father of immunology. 
  • Jenner was the pioneer of the smallpox vaccine, as his experiments opened the pathway of the discovery of the immune system. 
  • He observed the immune capabilities by injecting pus of an infected person to a healthy host. 
  • The healthy person was not infected rather the antigen in the pus activated the immune response.

So, the correct answer is option C.

The term active immunity means

  1. increasing rate of heart beat

  2. increasing quantity of blood

  3. resistance developed after the entry of antigen into the body

  4. resistance developed before the entry of antigen into the body.


Correct Option: C
Explanation:

Active immunity involves the active functioning of the person's own immune system leading to the synthesis of antibodies on the entry of the antigens into the body.

An organism's immune system will rapidly respond to an antigen it has seen before. This secondary response activates a subset of lymphoid cells leading to a rise in antibody titer.

The subpopulation responsible for the initiation of this response is the

  1. Memory B-cell.

  2. Memory T-cell.

  3. NK-cell.

  4. Plasma cell.


Correct Option: A
Explanation:



Organism's immune system respond to an antigen rapidly to an antigen that it has tackled before, this is called secondary response/immunity. These cells are memory B cells, that get activated/proliferate in response to helper T cells 
So, the correct answer is 'Memory B-cell'

According to ................. theory, the resistance of body decreases with the increase in age.

  1. Immunity theory

  2. Collagen theory

  3. Both A and B

  4. None of the above


Correct Option: A
Explanation:
The immune system theory of aging is that the rate of aging is largely controlled by the immune system. As one ages, the numbers of critical cells in the immune system decrease and become less functional, thereby the resistance of the body decreases.
Thus, the correct answer is option (A).

Which one of the following statements is correct with respect to immunity ?

  1. The antibodies against small pox pathogen are produced by T-lymphocytes

  2. Antibodies are protein molecules each of which has four light chains

  3. Rejection of a kidney graft is the function of B-lymphocytes

  4. Preformed antibodies need to be injected to treat the bite by a viper snake


Correct Option: D

Study the given table and identify the incorrect matches.

(i) Malaria-mosquito relationship Ronald Ross
(ii) Rickettsial disease Syphilis, Trichinosis
(iii) Antibodies Immunity
(iv) Anti-retroviral drugs Azidothynidine, Didanosine
(v) Analgesics Gentamicin, Neomycin
  1. (i) and (iv)

  2. (ii) and (v)

  3. (iii) and (iv)

  4. (i) and (iii)


Correct Option: B
Explanation:

The Rickettsiae are a diverse group of bacteria some of which can be transmitted to humans via the bites of fleas, lice, ticks or mites. Several Rickettsia species present in Australia are capable of causing disease in people. 
Syphilis is a bacterial infection usually spread by sexual contact. The disease starts as a painless sore typically on your genitals, rectum or mouth. Syphilis spreads from person to person via skin or mucous membrane contact with these sores.
Trichinosis (trik-ih-NO-sis), sometimes called trichinellosis, is a type of roundworm infection. Roundworm parasites use a host body to live and reproduce. Occurring primarily among meat-eating animals (carnivores) especially bears, foxes and walruses the infection is acquired by eating roundworm larvae in raw or undercooked meat. 
An analgesic, or painkiller, is any member of the group of drugs used to achieve analgesia relief from pain.  Analgesic drugs act in various ways on the peripheral and central nervous systems. They are distinct from anesthetics, which reversibly eliminate sensation. Analgesics include paracetamol, the non-steroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone.
Gentamicin is an aminoglycoside antibiotic composed of a mixture of related gentamicin components and fractions and is used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms.
Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops. The discovery of neomycin dates back to 1949. It was discovered in the lab of Selman Waksman, who was later awarded the Nobel Prize in Physiology or Medicine in 1951. Neomycin belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds. 

So, the correct answer is option B.

In which of the following situations, there is a risk factor for children acquiring erythroblastosis foetalis?

  1. Mother is Rh -ve and father is Rh -ve.

  2. Mother is Rh -ve and father is Rh +ve.

  3. Mother is Rh +ve and father is Rh +ve.

  4. Mother is Rh +ve and father is Rh -ve.


Correct Option: B
Explanation:
Erythroblastosis fetalis also called hemolytic disease of the newborn, type of anemia in which the red blood cells (erythrocytes) of a fetus are destroyed in a maternal immune reaction resulting from a blood group incompatibility between the fetus and its mother. This happens during second pregnancy when the mother's immune system is already sensitized to Rh$^+$ antigens present on the blood cells of the foetus during the first pregnancy. The Rh gene being dominant, the feotus will be Rh$^+$ if anyone of the parent is Rh$^+$.
 So, the correct answer is "Mother is Rh-ve and father is Rh+ve."