Tag: soldiers of defense

Questions Related to soldiers of defense

Removal of calcium from freshly collected blood will

  1. Prevent clotting

  2. Result in clotting

  3. Prevent oxidation of haemoglobin

  4. Cause haemolysis


Correct Option: A
Explanation:

Clotting requires calcium ions ($Ca2^+$), which is why blood banks use a chelating agent to bind the calcium in donated blood, so the blood will not clot in the bag.

Mineral essential for the coagulation of blood is

  1. Potassium

  2. Magnesium

  3. Calcium

  4. Sodium


Correct Option: C
Explanation:

All the reactions which happen during the clotting process require calcium ions for their occurrence. Calcium works together with vitamin K and a protein called as fibrinogen in the clotting cascade. Without adequate levels of calcium and vitamin K, blood will take longer to clot and if both nutrients are missing it could be fatal. Therefore, the correct answer is option C.

The vitamin essential for the synthesis of prothrombin is 

  1. Vitamin K

  2. Vitamin E

  3. Vitamin A

  4. Vitamin D


Correct Option: A
Explanation:

Prothrombin is a precursor of the clotting factor thrombin. Prothrombin forms thrombin in the cascade clotting reaction. It is produced in the liver cells in the presence of vitamin K.

The blood does not clot inside the body because of

  1. Oxygenation of blood

  2. Movement of blood

  3. Heparin in blood

  4. Absence of fibrinogen in blood


Correct Option: C
Explanation:
A blood clot is actually the thickened mass formed by the blood platelets and stops the blood profusely out of any cuts or wounds. However, in general and in healthy condition blood does not form clots inside the body due to the presence of heparin an anticoagulant that is secreted by the basophils and mast  cells of the blood. Since, this is released into the blood vessels it prevents the formation of clots in them
So, the correct answer is 'Heparin in blood'

Which option is correct for the formation of intrinsic factor-X activator complex for blood coagulation?

  1. Activated Christmas factor + AHG + phospholipid + $Ca^{+2}$

  2. Inactivated Christmas factor + AHG + phospholipid +$Ca^{+2}$

  3. Convertin + AHG + $Ca^{+2}$+ FSF

  4. Phospholipid - protein complex + Proconvertin


Correct Option: A
Explanation:

The Hageman factor XII is activated when it comes in contact with a damaged blood vessel. The activated Hageman factor activates the factor XI. The activated factor XI acts on Chrishmas factor IX to form activated IXa. Factor IXa combines with AHG VIII phospholipid and calcium ions to form a complex called intrinsic factor X activator complex. Thus the correct answer is option A.

Match the following Columns I, II with III.

Column I(Common name) Column II(Roman numerical designation) Column III(Activation product)
A. Prothrombin 1. I (i) Convertin
B. Proconvertin 2. V (ii) Fibrin
C. Fibrinogen 3. II (iii) Thrombin
D. Proaccelerin 4. VII (iv) Accelerin
  1. A- 3- (iii), B- 4- (i), C- 1- (ii), D- 2- (iv)

  2. D- 4- (ii), B- 3- (iii) C- 2- (iv), A- 1- (i)

  3. C- 3- (iii), A- 4- (ii), B- 1- (iv), D- 2- (i)

  4. A- 3- (iii),C-  4- (i), D- 2- (ii), B- 1- (iv)


Correct Option: A
Explanation:

The following enzymes are involved in the mechanism of blood clotting in human.

Column I(Common name) Column II(Roman numerical designation) Column III(Activation product)
A. Prothrombin $3.$ II (iii) Thrombin
B. Proconvertin $4.$ VII (ii) Convertin
C. Fibrinogen $1.$ I (ii) Fibrin
D. Proaccelerin $2.$ V (iv) Accelerin

Fill in the blanks with suitable words given below:
The liquid part of coagulated blood is known as _________

  1. Serum

  2. Fibrinogen

  3. Hemoglobin

  4. Pulmonary

  5. Sphygmomanometer

  6. Ventricles


Correct Option: A
Explanation:

The liquid part of coagulated blood is known as serum. It is the liquid portion of blood clot . It includes all proteins not used in clotting of blood and all the electrolytes, hormones, antibodies, antigens etc..

Hence, the correct answer is 'Serum' .

Choose the correct answer from the alternatives given.
Which of the following ions is involved in blood clotting?

  1. $K^+$

  2. $Na^+$

  3. $Fe^{+++}$

  4. $Ca^{++}$


Correct Option: D
Explanation:

Blood coagulation is a complex biochemical process involving platelets and many proteins (enzymes).  Calcium is involved at several steps in the blood clotting, including the activation of the platelets, activation of clotting factors and enzymes which are present in the blood in inactive form. The $Ca^{++}$ ions bind with prothrombin and covert it into active form thrombin. The thrombin in turn converts fibrinogen into fibrin (a thread like protein) which traps red blood cells and helps in the formation of clot.

So, the correct option is '$Ca^{++}$'.

Sodium oxalate prevents blood clotting due to

  1. Blocking of fibrinogen transformation

  2. Covering RBC

  3. Inhibiting activity of clotting factor of plasma

  4. Combining with calcium ions of blood


Correct Option: D
Explanation:

Sodium oxalate, like citrates, can be used to remove calcium ions (Ca${^2}$${^+}$) from blood plasma. It thus prevents blood from clotting. In the presence of calcium ions and other clotting factors, factor X activates an enzyme called prothrombin activator. This enzyme then converts the plasma protein prothrombin into thrombin. Thrombin is an enzyme that, in turn, converts fibrinogen to fibrin.