Tag: soldiers of defense

Questions Related to soldiers of defense

Thrombokinase is associated with

  1. Ellimination of urea and other excreatory products from the body.

  2. Production of erythrocytes from the bone marrow.

  3. Pulmonary and systematic circulation.

  4. Cardiac cycle and its regulation

  5. Enzymatic reactions in coagulation of blood.


Correct Option: E
Explanation:

Thrombokinase is a substance present in platelets which are necessary for coagulation of blood. Thromboplastin helps in the conversion of prothrombin to thrombin in the presence of calcium which is the vital step in coagulation of blood.

Hence, the correct option is E.

Which one has no clotting property?

  1. Blood

  2. Lymph

  3. Tissue fluid

  4. None of the above.


Correct Option: A

Blood agglutination tests are used in

  1. Antigen antibody reaction

  2. Animal relations

  3. Immunity

  4. None of the above


Correct Option: A
Explanation:
Blood agglutination tests are used in Antigen-antibody reactions. The clumping of particles is called as agglutination. Clumping occurs when an antigen is mixed with its corresponding antibody. When people are given blood transfusions of the wrong blood group, the antibodies react with the incorrectly transfused blood group and as a result, the erythrocytes clump up and stick together causing them to agglutinate 
So, the correct answer is 'Antigen-antibody reaction'.

Blood precipitation test was proposed by

  1. Wallace

  2. Nuttal

  3. Bateson

  4. Needham


Correct Option: A
Explanation:
Blood precipitation test was proposed by Wallace. Blood precipitation reactions are based on the interaction between antibodies and antigens. They are based on two soluble reactants (Antigen and antibody) that come together to make one insoluble product(Antigen-Antibody complex), the precipitate. 
So, the correct answer is 'Wallace'.

Conversion of fibrinogen to fibrin is catalysed by

  1. Thrombin

  2. Prothrombin

  3. Thromboplastin

  4. All of these


Correct Option: A
Explanation:
Thrombin catalyzes the conversion of fibrinogen (factor I)—a soluble plasma protein into long, sticky threads of insoluble fibrin . The fibrin threads form a mesh that traps platelets, blood cells, and plasma.The fibrin mesh work begins to contract in a short period of time and prevents blood loss. 
So, the correct answer is 'Thrombin'

During the process of blood coagulation, vitamin k helps in

  1. The formation of thromboplastin

  2. The conversion of fibrinogen to fibrin

  3. The conversion of prothrombin to thrombin

  4. The formation of prothrombin


Correct Option: D
Explanation:

Vitamin K helps in the synthesis of prothrombin in the liver.

So, the correct answer is 'The formation of prothrombin'

In the clotting mechanism pathway, thrombin activates the factors

  1. XI, VIII, V

  2. XI, IX, X

  3. VIII, X, V

  4. only XIII


Correct Option: D
Explanation:

In the blood coagulation pathway thrombin activates Factor XIII to XIIIa that helps in binding of fibrin monomers to form the stable fibrin filament.

So, the correct answer is 'only XIII'

Which proteolytic enzyme induces lysis of fibrin during fibrinolysis?

  1. Fibrin

  2. Thrombin

  3. Plasmin

  4. Platelet factor VIII


Correct Option: C
Explanation:

Plasmin is the proteolytic enzyme that induces lysis of fibrin to fibrin degradation products during fibrinolysis (enzymatic breakdown of fibrin during blood clots)

So, the correct answer is 'Plasmin'

Mark the pair of substances among the following which is essential for coagulation of blood.

  1. Heparin and calcium ions

  2. Calcium ions and platelet factors

  3. Oxalates and citrates

  4. Platelet factors and heparin


Correct Option: B
Explanation:

Calcium ions and platelets are essential factors for clotting of blood. During some injury, the platelets release inactivated platelet factors that are involved in the activation of other factors involved in the formation of clots in the blood. Calcium ions in the blood catalyze the activation of many factors involved in clot formation like factor VIII, factor IX, factor V and factor XIII.

Thus, the correct answer is 'Calcium ions and platelet factors.'

Which of these are necessary for initiation of blood clotting process?

  1. Prothrombinase and thrombin

  2. Tissue factor hageman factor and $Ca^{2+}$

  3. Prothrobinase and $K^{2+}$

  4. Prothrobinase , tissue factor and $Ca^{2+}$


Correct Option: B
Explanation:

There are two processes that can initiate clotting

  1. A very rapid process the so-called extrinsic pathway 
  2. A slower but larger intrinsic pathway
In the extrinsic pathway- Damaged cells display a surface protein called tissue factor
In the intrinsic pathway- Factor 12 (XII) (also called the Hageman factor) circulates in the blood.
Calcium ions are required for the promotion or acceleration of blood clotting pathways
So correct option is B, Tissue factor hageman factor and $Ca^{2+}$.