Tag: soldiers of defense
Questions Related to soldiers of defense
An anticoagulant is
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Heparin
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Hirudin
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EDTA
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All of the above
Heparin is a natural anticoagulant in the body. Hirudin is an anticoagulant produced by leech while sucking the blood of the host. EDTA acts as an anticoagulant by removing calcium ions from the blood and thus chelates with them.
During blood clotting, fibrin is produced by
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Thrombokinase
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Prothrombin
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Liver
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Proteolysis
Which of the following is an anticoagulant and checks blood coagulation in blood vessels?
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Prothrombin
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Globulin
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Thromoboplastin
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Heparin
Heparin is a natural anticoagulant produced in the liver and helps in checking the clotting of blood inside blood vessels.
During blood clotting, which of the following is used?
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Co
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$Ca^{++}$
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$Na^+$
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$Cl^-$
Blood clotting (coagulation) is the process by which blood vessels repair ruptures after injury. Calcium works together with vitamin K and a protein, called as fibrinogen in the clotting cascade, which forms fibrin. The fibrin hardens very quickly to form a scab over the wound.
Prothrombin is found in
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Intestine and helps in cellulose digestion
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Liver and helps in production of bile
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Blood and gives red colour to blood
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Blood and helps in blood clotting
Prothrombin is a plasma protein which is converted into thrombin in the presence of thromboplastin released by platelets at the site of injury. The thrombin then converts protein fibrinogen into insoluble fibrin and thus aids in blood clotting.
Which of the following does not play a role in blood coagulation?
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Vitamin K
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Vitamin D
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Calcium ions
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Fibrinogen
Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a clot. The activation of some of the enzymes in the coagulation cascade is dependent on vitamin K. In the presence of other plasma proteins (clotting factors) and calcium ions, this leads to the activation of a protein called as factor X.
The function of vitamin K is in
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Regulation of calcium and phosphorus metabolism
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Blood clotting
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Respiration
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Carbohydrate metabolism
Vitamin K plays an important role in blood clotting. It is required by the body for the synthesis of prothrombin by the liver. Prothrombin is a plasma protein which gets converted into thrombin during the clotting process and thus helps in clotting mechanism. Thus, the correct answer is option B.
An anticoagulant used for preventing clotting in vitro is sodium oxalate. It prevents clot formation by
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Combining with cations in the blood
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Inhibiting clotting factor VIII activity
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Getting itself deposited over the surface of ROC
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Blocking the fibrinogen activity
Sodium oxalate (like citrates) can be used to remove calcium ions (Ca$^{2+}$) from the blood plasma. The oxalate prevents clotting by forming insoluble calcium salts, thus removing ionic calcium (or cations).
Therefore, the correct answer is option A.
In human, the prothrombin required for blood clotting is produced in
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Liver
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Stomach
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Pancreas
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Spleen
Prothrombin is a plasma glycoprotein produced in the liver. It gets converted into thrombin by a clotting factor prothrombinase which further transforms fibrinogen into fibrin which combines with platelets to form clot.
Blood doesn't clot in the absence of vitamin K because it is
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An essential component of the clot
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An essential component of the platelets
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Essential for synthesis of prothrombin
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Essential for synthesis of fibrinogen
Blood clotting factors are needed for blood to clot (coagulation). Prothrombin, or factor II, is one of the clotting factors made by the liver. Vitamin K is needed to make prothrombin and other clotting factors. So, blood does not clot in the absence of Vitamin K because it is essential for the synthesis of prothrombin and not because it is an essential component of the clot, platelets or essential for fibrinogen.