Tag: biotechnology

Questions Related to biotechnology

The immunoglobulin involved in the type II hypersensitivity reactions is

  1. IgA.

  2. IgM.

  3. IgG.

  4. Both B and C.


Correct Option: D

Patch test can be related to 

  1. Hypersensitivity I.

  2. Hypersensitivity II.

  3. Hypersensitivity III.

  4. Hypersensitivity IV.


Correct Option: D

Cytotoxic type II reactions are also known as

  1. Hypersensitivity IV.

  2. Hypersensitivity III.

  3. Hypersensitivity II.

  4. Hypersensitivity I.


Correct Option: C

The major type of delayed type hypersensitivity is (are)

  1. Arthus Reaction.

  2. Tuberculin.

  3. Contact dermatitis.

  4. Both B and C.


Correct Option: D

IgE antibodies are known as cytotropic antibodies because

  1. They are fixed on mast cell and basophils.

  2. They are fixed on eosinophils.

  3. They are fixed on neutrophils.

  4. None of the above.


Correct Option: A

Arrange the given statement in the correct order according to type II hypersensitivity reactions.
a) IgG or IgM antibodies react with the antigen on the surface of cells.
b) Opsonization and phagocytosis. 
c) Activation of the complement cascade.
d) Cell death and lysis.

  1. a,b,c,d

  2. a,c,b,d

  3. a,d,c,b

  4. None of the above


Correct Option: B

Tuberculin, a type of hypersensitivity IV was given by ____________

  1. Louis Pasteur.

  2. Alexender Flemming.

  3. Robert Koch.

  4. None of the above.


Correct Option: C

Which of the following cell releases a hydrolytic enzyme during type IV hypersensitivity reaction?

  1. Macrophages

  2. T killer cells

  3. T helper cells

  4. All of the above


Correct Option: A
Explanation:
Type IV hypersensitivity Is a type of cell-mediated response. CD4+ helper T cells recognize antigen in a complex with major histocompatibility complex  Class II. The antigen-presenting cells are macrophages that secrete IL-12, which stimulates the proliferation of further CD4+ Th cells which secrete IL-2 and interferon gamma. This further inducing the release of other Th cytokines, thus mediating the immune response. Activated CD8+ T cells kill target cells on contact, whereas activated macrophages produce hydrolytic enzymes. Thus the correct answer is option A. 

Which of the following step is not a part of hypersensitivity type IV reaction?

  1. Sensitization

  2. Antigen presentation

  3. Phagocytosis

  4. All of the above


Correct Option: D

Hypersensitivity type IV reaction does not involve 

  1. Phagocytosis.

  2. Antibodies.

  3. Lymphokines.

  4. None of the above.


Correct Option: B