Chemistry · Biology

Pharmacology and Therapeutics

1,643 Questions

Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.

Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests

Pharmacology and Therapeutics Questions

Multiple choice

The anticonvulsants are used in the treatment of epileptic seizures. Which among the following is an anticonvulsant?

  1. Fosamax

  2. Gabapentin

  3. Gardasil

  4. Geodon
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Gabapentin is an anti-epileptic medication, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.It is used to treat seizures caused by epilepsy in adults and children who are at least 12 years old.

Multiple choice

There are many types of muscle relaxants for pain relief. Among the following, --------------------- is a muscle relaxant .

  1. ciprofloxacin

  2. claritin

  3. crestor

  4. cyclobenzaprine
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Cyclobenzaprine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Multiple choice

Which of the following compounds is used as a sedative and hypnotic drug ?

  1. Chloroacetyl chloride

  2. Chloral

  3. Chloral hydrate

  4. N-chloro tosylamide sodium salt
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Chloral hydrate is a sedative and hypnotic drug as well as a chemical reagent and precursor. The name chloral hydrate indicates that it is formed from chloral (trichloroacetaldehyde) by the addition of one molecule of water. Its chemical formula is C2H3Cl3O2.

Multiple choice

Which of the following cause(s) vasodilation in kidneys?

  1. Nonsteroidal anti-inflammatory drugs

  2. ADH

  3. Epinephrine

  4. Prostaglandins

  5. Angiotensin II
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Prostaglandins are powerful vasodilators and there is a normal tonic level of vasodilation in the renal blood vessels. It is caused by prostaglandins.

Multiple choice

Headaches can often be effectively relieved by over-the-counter medication, without necessitating a physician’s oversight. However, doctors warn against employment of this simple strategy for recurring or particularly long-lasting headaches, even if such medication can provide relief. Since such headaches are often symptomatic of more serious maladies, sufferers are strongly advised instead to consult their physicians.

Which of the following conclusions is most strongly supported by the statements above?

  1. The greater the pain associated with a particular headache, the more serious the underlying cause.

  2. In some cases physicians advise against seeking immediate relief from pain.

  3. Some headaches cannot be relieved with over-the-counter medications.

  4. Physicians tend to focus less on pain relief rather than on other physical symptoms.

  5. Over-the-counter medication cannot provide effective relief of a headache if the underlying cause is a serious malady.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

(1) The greater the pain associated with a particular headache, the more serious the underlying cause.

There's no mention of a connection between the headache severity and severity of its underlying cause.

(2) In some cases physicians advise against seeking immediate relief from pain.
In some cases (headaches with more serious underlying causes), physicians advise against seeking immediate relief (OTC meds) and strongly advise that individuals consult their physicians.
(3) Some headaches cannot be relieved with over-the-counter medications.
"..even if such medication can provide relief" suggests that this statement cannot be supported.
(4) Physicians tend to focus less on pain relief rather than on other physical symptoms. -There's no mention of this.
(5) Over-the-counter medication cannot provide effective relief of a headache if the underlying cause is a serious malady. The text says "even if such medication can provide relief." However there's no distinction between more serious or less serious maladies.

Multiple choice

Ezetimibe reduces blood cholesterol levels by inhibiting __________.

  1. the HMG-Co A reductase

  2. absorption of cholesterol by intestine

  3. secretion of cholesterol-containing VLDL by liver

  4. activity of LDL receptor

  5. activity of cholesterol 7 alpha-hydroxylase
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Ezetimibe reduces blood cholesterol levels by inhibiting absorption of cholesterol by intestine by blocking uptake via Niemann-Pick C-like 1 protein.

Multiple choice

Norplant is

  1. an oral pill

  2. tubectomy

  3. subcutaneous implants

  4. Depo-Provera

  5. a condom
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Under the skin, implantation of synthetic progesterone, which acts almost similar to oral pills

Multiple choice

Which of the following is not correctly matched?

  1. Chloroquine: Antimalarial drug

  2. Luminal: Hypnotic drug

  3. Aspirin: Phenylalanyl aspartic acid

  4. Fluconazole: Antifungal drug

  5. Ibuprofen: 2-(4-isobutylphenyl) propionic acid
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The common chemical name of aspirin is acetylsalicylic acid.

Multiple choice

Which of the following pairs is correctly matched?

  1. Alitame: Enzyme

  2. Chloramphenicol: Natural antimicrobial agent

  3. Thyroxine: Iodine containing hormone

  4. Omeprazole: Food preservative

  5. Ranitidine: Antifertility drug
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Thyroxine is an iodine containing hormone secreted by the thyroid gland that increases the rate of cell metabolism and regulates growth.