Chemistry ยท Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
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taxanes
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antimetabolites
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cytotoxic antibiotics
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alkylating drugs
B
Correct answer
Explanation
Methotrexate is a chemotherapy agent that works by inhibiting dihydrofolate reductase, which is essential for DNA synthesis. It is classified as an antimetabolite.
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analgesic
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diuretic
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antipyretic
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neuromuscular blocker
D
Correct answer
Explanation
Succinylcholine is a depolarizing neuromuscular blocker that binds to nicotinic receptors at the neuromuscular junction, causing muscle paralysis. It is used for muscle relaxation during anesthesia and intubation. The question incorrectly describes it as 'slow acting' when it is actually rapid-acting, but the answer choice identifying it as a neuromuscular blocker is correct.
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reserpine
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hydralazine
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nifedepine
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metoprolol
C
Correct answer
Explanation
Nifedipine (misspelled as 'nifedepine') is a dihydropyridine calcium channel blocker that inhibits calcium influx into vascular smooth muscle and cardiac cells, causing vasodilation. Reserpine is an adrenergic inhibitor, hydralazine is a direct vasodilator, and metoprolol is a beta-blocker. Only nifedipine belongs to the calcium channel blocker class.
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antimetabolites
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taxanes
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immunosuppressants
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alkylating drugs
D
Correct answer
Explanation
Cyclophosphamide is a nitrogen mustard derivative that works by cross-linking DNA, which classifies it as an alkylating agent used in chemotherapy.
A
Correct answer
Explanation
P276 is a cyclin-dependent kinase inhibitor developed by Piramal Life Sciences, which underwent clinical trials for the treatment of head and neck cancer around 2008.
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Calm the nerves
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Cure allergies
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Relieve pain
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Lower body temperature
C
Correct answer
Explanation
Analgesics are a class of drugs specifically designed to relieve pain without causing the loss of consciousness.
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Calm the nerves
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Cure allergies
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Relieve pain
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Lower body temperature
D
Correct answer
Explanation
Antipyretics are medications specifically designed to reduce fever by lowering body temperature.
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tear gas
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a fertilizer
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a pain killer
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none of these
C
Correct answer
Explanation
Acetylsalicylic acid is the chemical name for aspirin, which is widely used as a pain reliever, anti-inflammatory, and fever reducer.
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Stomach ulcers
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Diarrhoea
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Cancer
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Paralysis
D
Correct answer
Explanation
Metanil yellow is toxic and carcinogenic
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ascities frequently responds well to diuretics
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bowel obstruction is frequently managed medically using subcutaneous medication
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opioid analgesics should be avoided
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lymphoedema is rare
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pattern of spread for epithelial ovarian cancer is primarily extra-abdominal
B
Correct answer
Explanation
Bowel obstruction is a obstruction of the intestines, preventing the normal transit of the products of digestion. It is common and is usually managed medically using subcutaneous medication given via a syringe driver.
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analgesics
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endorphins
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neurotoxins
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neurins
B
Correct answer
Explanation
This option is correct because endorphins are produced during the time of physical/emotional stress for example: child birth, etc.
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magnesium benzoate
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magnesium carbonate
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magnesium citrate
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magnesium nitrate
C
Correct answer
Explanation
Magnesium citrate, a magnesium salt of citric acid, is a chemical agent used medicinally as a saline laxative and to completely empty the bowel prior to a major surgery or colonoscopy.
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To cure bronchitis
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To cure leprosy
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To lower high blood pressure
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In chronic dysentery
C
Correct answer
Explanation
Rauwolfia serpentina, also known as Sarpagandha, contains alkaloids like reserpine which are used to treat hypertension (high blood pressure).
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To cure bronchitis
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To cure leprosy
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To lower high blood pressure
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In chronic dysentery
B
Correct answer
Explanation
The oil extracted from the seeds of the Chaulmoogra tree (Hydnocarpus wightianus) has been used historically as a treatment for leprosy.
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Antiseptic
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Antacid
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Analgesic
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None of these
B
Correct answer
Explanation
Antacids are substances that neutralize excess stomach acid, which is the primary cause of indigestion. Antiseptics prevent infection, and analgesics are painkillers.