Biology

Molecular Genetics

917 Questions

Molecular genetics explores the mechanisms of genetic information transfer, including DNA replication, transcription, and translation. It is a core component of biology syllabi. These concepts frequently appear in general science sections of major competitive exams.

DNA replicationTranscription processTranslation processRNA typesCentral dogma

Molecular Genetics Questions

Multiple choice
  1. Only P

  2. Only Q

  3. Only R

  4. Only P and Q

  5. Only Q and R

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Nucleic acid based detection systems were greatly improved following the development of the polymerase improved following the development of the polymerase chain reaction (PCR). PCR is able to detect pathogens by targeting their genetic material (RNA/DNA). Real time PCR (RT-PCR) is used to combine amplification, detection and quantification in a single step for RNA as target. Immunocapture PCR (IC-PCR) is used to combine the advantages of serology and is a very sensitive method of detection the diseases by targeting both DNA & RNA as genetic material. Multiplex PCR (IC-RT-PCR) allows for simultaneous and sensitive detection of different DNA & RNA as genetic material in the detection of plant diseases in a single reaction.

Multiple choice
  1. Ribozyme

  2. Catalytic poisons

  3. Catalytic promoters

  4. Inhibitors

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Substances which destroy the activity of the catalyst by their presence are known as catalytic poisons. (i) For example, the presence of traces of arsenious oxide (As2O3) in the reacting gases reduces the activity of platinized asbestos which is used as catalyst in contact process for the manufacture of sulphuric acid.

Multiple choice
  1. The sigma-1 receptor

  2. Inositol trisphosphate receptor

  3. The sigma-2 receptor

  4. The androgen receptor

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor.The main function of the androgen receptor is as a DNA-binding transcription factor that regulates gene expression. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

Multiple choice
  1. in-vitro virus high-throughput sequencing

  2. RNAP sequencing

  3. transmission electron microscopy DNA sequencing

  4. microfluidic Sanger sequencing

  5. sequencing with mass spectrometry

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

A method has been developed to analyze full sets of protein interactions using a combination of 454 pyrosequencing and an in-vitro virus mRNA display method. Specifically, this method covalently links proteins of interest to the mRNAs encoding them, then detects the mRNA pieces using reverse transcription PCRs.

Multiple choice
  1. RNA

  2. chromosomes

  3. genes

  4. peptides

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Genes are the functional segments of DNA that code for specific proteins and determine hereditary traits. Chromosomes are structures containing many genes, RNA is a nucleic acid, and peptides are protein chains.

Multiple choice
  1. DNA region which codes for a single RNA

  2. DNA region which codes for protein

  3. DNA region that codes for a single RNA or protein

  4. Fragment of chromosomes

  5. None of these

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

It is most appropriate answer that gene is the region of DNA that codes for a single RNA or protein. Hence, this option is the correct answer.

Multiple choice
  1. DNA and lipid

  2. RNA and protein

  3. RNA and lipid

  4. DNA and protein

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Ribosomes are cellular organelles composed of ribosomal RNA (rRNA) and proteins. The rRNA provides the structural framework and catalytic activity, while proteins help in assembly and function. This combination makes ribosomes ribonucleoprotein complexes essential for protein synthesis.

Multiple choice
  1. mRNA

  2. rRNA

  3. gRNA

  4. none of these

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Messenger RNA (mRNA) typically constitutes 3-5% of total cellular RNA in most cells. It has the shortest half-life of all RNA types because it's continuously synthesized and degraded during protein synthesis. rRNA makes up about 80-85% while tRNA constitutes about 10-15% of total cellular RNA.

Multiple choice
  1. structure of protein

  2. total protein encoded by DNA of an organism

  3. total proteins synthesized in mitochondria of a cell

  4. none of these

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The proteome refers to the entire set of proteins encoded by an organism's genome - it is the protein complement of the genome. It is not limited to protein structure, mitochondrial proteins, or any subset.