Biology
Molecular Genetics
917 Questions
Molecular genetics explores the mechanisms of genetic information transfer, including DNA replication, transcription, and translation. It is a core component of biology syllabi. These concepts frequently appear in general science sections of major competitive exams.
DNA replicationTranscription processTranslation processRNA typesCentral dogma
Molecular Genetics Questions
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ribosomal RNA
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messenger RNA
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transfer RNA
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soluble RNA
B
Correct answer
Explanation
The type of RNA specifically responsible for directing the proper sequence of amino acids in protein sythesis is messenger RNA.
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only protein
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only DNA
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only RNA
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both RNA & DNA
D
Correct answer
Explanation
3 to 5 strand of DNA generally acts a template for the synthesis of both RNA & DNA.
C
Correct answer
Explanation
The anticodon present in tRNA which can carry methionine is UAC.
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3 to 5
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5 to 3
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3 to 3
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5 to 5
B
Correct answer
Explanation
RNA polymerise catalyse elongation in 5 to 3 direction.
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Only P
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Only Q
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Only R
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Only P and Q
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Only Q and R
E
Correct answer
Explanation
Nucleic acid based detection systems were greatly improved following the development of the polymerase improved following the development of the polymerase chain reaction (PCR). PCR is able to detect pathogens by targeting their genetic material (RNA/DNA).
Real time PCR (RT-PCR) is used to combine amplification, detection and quantification in a single step for RNA as target.
Immunocapture PCR (IC-PCR) is used to combine the advantages of serology and is a very sensitive method of detection the diseases by targeting both DNA & RNA as genetic material.
Multiplex PCR (IC-RT-PCR) allows for simultaneous and sensitive detection of different DNA & RNA as genetic material in the detection of plant diseases in a single reaction.
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Ribozyme
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Catalytic poisons
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Catalytic promoters
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Inhibitors
B
Correct answer
Explanation
Substances which destroy the activity of the catalyst by their presence are known as catalytic poisons. (i) For example, the presence of traces of arsenious oxide (As2O3) in the reacting gases reduces the activity of platinized asbestos which is used as catalyst in contact process for the manufacture of sulphuric acid.
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The sigma-1 receptor
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Inositol trisphosphate receptor
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The sigma-2 receptor
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The androgen receptor
D
Correct answer
Explanation
The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor.The main function of the androgen receptor is as a DNA-binding transcription factor that regulates gene expression. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
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in-vitro virus high-throughput sequencing
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RNAP sequencing
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transmission electron microscopy DNA sequencing
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microfluidic Sanger sequencing
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sequencing with mass spectrometry
A
Correct answer
Explanation
A method has been developed to analyze full sets of protein interactions using a combination of 454 pyrosequencing and an in-vitro virus mRNA display method. Specifically, this method covalently links proteins of interest to the mRNAs encoding them, then detects the mRNA pieces using reverse transcription PCRs.
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RNA
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chromosomes
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genes
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peptides
C
Correct answer
Explanation
Genes are the functional segments of DNA that code for specific proteins and determine hereditary traits. Chromosomes are structures containing many genes, RNA is a nucleic acid, and peptides are protein chains.
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DNA region which codes for a single RNA
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DNA region which codes for protein
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DNA region that codes for a single RNA or protein
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Fragment of chromosomes
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None of these
C
Correct answer
Explanation
It is most appropriate answer that gene is the region of DNA that codes for a single RNA or protein. Hence, this option is the correct answer.
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DNA and lipid
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RNA and protein
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RNA and lipid
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DNA and protein
B
Correct answer
Explanation
Ribosomes are cellular organelles composed of ribosomal RNA (rRNA) and proteins. The rRNA provides the structural framework and catalytic activity, while proteins help in assembly and function. This combination makes ribosomes ribonucleoprotein complexes essential for protein synthesis.
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mRNA
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rRNA
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gRNA
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none of these
A
Correct answer
Explanation
Messenger RNA (mRNA) typically constitutes 3-5% of total cellular RNA in most cells. It has the shortest half-life of all RNA types because it's continuously synthesized and degraded during protein synthesis. rRNA makes up about 80-85% while tRNA constitutes about 10-15% of total cellular RNA.
Match the following:
| |
|
| Group I |
|
|
Group II |
| P. Nalidixic acid |
1. Topoisomerase |
| Q. Erythromycin |
2. Peptide chain elongation |
| R. Cephalosporin |
3. Peptidoglycan synthesis |
| S. Sulphonamide |
4. Folic acid biosynthesis |
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P - 1, Q - 2, R - 3, S - 4
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P - 2, Q - 1, R - 3, S - 4
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P - 4, Q - 1, R - 2, S - 3
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P - 3, Q - 4, R - 2, S - 1
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P - 3, Q - 4, R - 1, S - 2
A
Correct answer
Explanation
Correct matching is P - 1, Q - 2, R - 3, S - 4.
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structure of protein
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total protein encoded by DNA of an organism
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total proteins synthesized in mitochondria of a cell
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none of these
B
Correct answer
Explanation
The proteome refers to the entire set of proteins encoded by an organism's genome - it is the protein complement of the genome. It is not limited to protein structure, mitochondrial proteins, or any subset.