Multiple choice

Premature translation termination mediates triosephosphate isomerase mRNA degradation. Which one of the following types of mutations is most likely to lead to premature termination of translation?

  1. Exon skip

  2. Single base change in a promoter

  3. Deletion of an entire gene

  4. Deletion of three bases from DNA

  5. Insertion of a single base into DNA

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Insertion of one base will alter the reading frame and usually leads to a stop codon eventually.