Biology
Molecular Genetics
851 Questions
Molecular genetics explores the mechanisms of genetic information transfer, including DNA replication, transcription, and translation. It is a core component of biology syllabi. These concepts frequently appear in general science sections of major competitive exams.
DNA replicationTranscription processTranslation processRNA typesCentral dogma
Molecular Genetics Questions
A
Correct answer
Explanation
Exons are the coding regions of genes that contain the actual genetic information (protein-coding sequences). They are retained in mature mRNA after splicing and translated into proteins. The phrasing "information carrying genes" is slightly imprecise (exons are parts of genes, not genes themselves), but the core meaning is correct.
B
Correct answer
Explanation
Introns are non-coding regions within genes that are removed during RNA splicing. They do NOT carry genetic information for protein synthesis - that's the job of exons. The statement correctly identifies that introns are not information-carrying sequences.
A
Correct answer
Explanation
Introns are "interrupting" or non-coding sequences that break up the coding regions (exons) within a gene. They interrupt the continuous protein-coding sequence and must be removed by splicing. The term "interrupting sequences" is an accurate description of their structural role.
A
Correct answer
Explanation
The Central Dogma of molecular biology states that genetic information flows from DNA to RNA to Proteins. DNA is transcribed into RNA, which is then translated into proteins. This fundamental principle correctly describes the directional flow of genetic information in cells.
A
Correct answer
Explanation
mRNA (messenger RNA) carries genetic information from DNA to ribosomes for protein synthesis. This is a fundamental concept in molecular biology - the 'central dogma' flows DNA → mRNA → protein. This statement is scientifically accurate.
A
Correct answer
Explanation
The first complete nucleotide sequence of a tRNA molecule was determined in 1965 by Robert W. Holley and colleagues at Cornell University, for alanine tRNA from yeast. This was a landmark achievement in molecular biology.
B
Correct answer
Explanation
Plant genes are composed of DNA (deoxyribonucleic acid), which is the primary molecule storing genetic information in cells. RNA (ribonucleic acid) plays important roles in gene expression and protein synthesis, but genes themselves are DNA sequences. The claim that genes are made of RNA is false.
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Mitochondria
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RNA
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Cell
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DNA
D
Correct answer
Explanation
DNA contains the complete genetic instructions for an organism's development and functioning, earning it the 'biological blueprint' designation. RNA carries protein blueprints, cells are basic structural units, and mitochondria produce energy - none serve as the master blueprint.
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deaminate
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degenerate
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universal
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commaless
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non-overlapping
B
Correct answer
Explanation
The genetic code is degenerate in that most amino acids are encoded by more than one codon.
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they terminate anticodons
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they are present at the beginning of mRNA
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they indicate initiation of translation
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they do not specify any amino acid
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they terminate mRNA
D
Correct answer
Explanation
It is true that nonsense codons do not code for any amino acid.
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proteins
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fatty acids
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fats
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carbohydrates
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glycogen
A
Correct answer
Explanation
An exon is any nucleotide sequence encoded by a gene that remains present within the final mature RNA product of that gene after introns have been removed. It helps in the synthesis of proteins.
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RNA polymerase
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RNA ligase
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DNA polymerase
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DNA ligase
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DNA methylase
A
Correct answer
Explanation
A sigma factor (σ factor) is a protein needed only for initiation of RNA synthesis. It is associated with RNA polymerase enzyme.
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code for non-essential amino acids
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code for initiator amino acid, which is removed later
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are never present in the RNA
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do not code for any amino acid
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code for some special amino acids
D
Correct answer
Explanation
It is true as these are used as stop codons and these terminate the growing amino acid chain wherever they are present.
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Anticodon consists of three nucleotides.
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Anticodon may pair with more than one codon.
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It is the basic unit of genetic code.
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tRNA is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length.
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The covalent attachment to the tRNA 3’ end is catalyzed by enzymes called aminoacyl tRNA synthetases.
C
Correct answer
Explanation
This statement is not true as codon, which is a sequence of three nucleotides on m-RNA, is the basic unit of genetic code.