Biology
Molecular Genetics
917 Questions
Molecular genetics explores the mechanisms of genetic information transfer, including DNA replication, transcription, and translation. It is a core component of biology syllabi. These concepts frequently appear in general science sections of major competitive exams.
DNA replicationTranscription processTranslation processRNA typesCentral dogma
Molecular Genetics Questions
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lncRNAdb
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SILVA
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GtRNAdb
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piRNABank
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Rfam
B
Correct answer
Explanation
SILVA is a comprehensive on-line resource for quality checked and aligned ribosomal RNA sequence data.
D
Correct answer
Explanation
Mg acts as a co-factor for Taq polymerase. With the increase of Mg, the specificity of Taq decreases.
C
Correct answer
Explanation
rRNA is synthesised by RNA polymerase I.
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5' capping
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3' polyadenylation
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RNA splicing
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All of the above
D
Correct answer
Explanation
Post-transcriptional modifications of pre-mRNA involve 5'capping, 3' polyadenylation and RNA splicing.
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Sn RNA
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t-RNA
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Both (1) and (2)
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m RNA
C
Correct answer
Explanation
Both Sn RNA and t-RNA are non protein coding genes and yield functional RNA as products.
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RNA
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Proteins
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RNA and proteins
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DNA
C
Correct answer
Explanation
Nucleolus is composed of both RNA and proteins.
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ΦX174
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TMV (Tobacco Mosaic virus)
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RSV (Rous Sarcoma virus)
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mumps virus
C
Correct answer
Explanation
RSV is a retrovirus and expresses gene by teminism.
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transformation
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transcription
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replication
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Both (3) and (2)
A
Correct answer
Explanation
Gene expression in bacteria takes place by transformation. The donor DNA is broken into one gene segment which enters the recipient cell, gets integrated into recipient genome and expresses itself.
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Transcription factors help in unwinding DNA.
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Transcription factors help in recognising promoter sequence.
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Transcription factors recognise ori site.
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Transcription factors are involved in proof reading of newly synthesised RNA.
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None of these
B
Correct answer
Explanation
Transcription factors help in recognising promoter sequence in template DNA where RNA polymerase binds.
A
Correct answer
Explanation
The codon AUG functions as a start codon and serves as a starting point for protein synthesis. It also codes for the amino acid methionine.
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Transcription
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Reverse Transcription
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Translation
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Translocation
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Transformation
B
Correct answer
Explanation
Reverse Transcription is the process of synthesis of double stranded DNA from single stranded RNA using the enzyme reverse transcriptase.
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Ribosomes
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Nucleoplasm
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Nucleolus
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r - RNA
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DNA
C
Correct answer
Explanation
Nucleolus helps to synthesise nucleoproteins.
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mRNA
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Genomic DNA
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Intron
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Exons
A
Correct answer
Explanation
A cDNA library is created by using reverse transcriptase to copy mRNA into DNA, which is subsequently cloned. Each cDNA is homologous to a distinct mRNA molecule.
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carries the information for more than one type of protein
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carries the information for a single type of protein
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contains codons of more than one cistron
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Both (1) and (3)
D
Correct answer
Explanation
Polycistronic mRNA contains codons of more than one cistron.
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at the promoter
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at the 5' end of the intron
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at the branch point of the intron
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at the 3' end of the intron
D
Correct answer
Explanation
The sequence at the 3' end is the splice acceptor (which includes AT preceded by a consensus sequence).