Multiple choice

Which of the following types of mutation is most likely to lead to premature termination of translation?

  1. Insertion of a single base into DNA

  2. Deletion of three bases from DNA

  3. Deletion of an entire gene

  4. Single base change in a promoter

  5. Exon skip

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Insertion of one base will alter the reading frame and usually leads to a stop codon eventually.