Biology

Human Immunity and Blood

2,096 Questions

Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.

Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology

Human Immunity and Blood Questions

Multiple choice

Directions: For the Assertion (A) and Reason (R) below, choose the correct alternative from the following. Assertion: In medical parlance with respect to blood groups, a person with a blood group of ‘O’ is called Universal Donor. Reason: A person with the ‘AB’ blood group can accept blood of all types, i.e., A, B, AB and O.

  1. Both A and R are true and R is the correct explanation of A.

  2. Both A and R are true but R is not the correct explanation of A.

  3. A is true but R is false.

  4. A is false but R is true.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Both A and R are true, but R is not the reason for A. Hence, option (2) is correct.

Multiple choice

Which of the following cells help in clotting of blood?

  1. Lymphocytes

  2. Erythrocytes

  3. Leucocytes

  4. Thrombocytes
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to stop bleeding by clumping and clotting blood vessel injuries. 

Multiple choice

Primary blood cells are formed in

  1. plasma

  2. bone marrow

  3. liver

  4. spleen

  5. -
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

All primary blood cells are produced and derived from multipotent cells in the bone marrow. These cells are known as hematopoietic stem cells.

Multiple choice

Kupffer cells are present in

  1. liver

  2. small intestine

  3. large intestine

  4. pancreas

  5. -
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Kupffer cells are phagocytic cells which form the lining of the sinusoids of the liver and are involved in the breakdown of red blood cells.

Multiple choice

Histamine is secreted by which of the following?

  1. Muscle cells

  2. Kupffer cells

  3. Nerve cells

  4. Mast cells

  5. -
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Mast cell is filled with basophil granules that are found in numbers in connective tissue. They release histamine and other substances during inflammatory and allergic reactions.

Multiple choice

Which of the following blood groups is the universal recipient?

  1. O

  2. AB

  3. A

  4. B

  5. -
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

A person having AB blood group is able to receive blood from a person having any other blood type. Group AB blood contains red blood cells that have both antigens A and B. Thus, it does not have reactive antibodies in its plasma to these antigens, which are found in some other blood types.

Multiple choice

Which of the following statements is false about allergic asthma?

  1. The relevant allergen that provokes allergic asthma in a given patient is diagnosed routinely by the use of RAST.

  2. It mainly affects children before the age of five.

  3. Th2 cells are found in bronchoalveolar lavage fluid.

  4. Allergic asthma is characterised by reversible airways obstruction.

  5. Ciclosporin therapy is helpful in severe cases.
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

RAST testing is not helpful as most patients are atopic and therefore, react to many environmental allergens. There is a better correlation of clinical relevant allergen with skin prick testing. This is used routinely, particularly in adults. 

Multiple choice

Which of the following statements about C3NeF is false?

  1. C3NeF is produced by the kidneys.

  2. C3NeF is an IgG class autoantibody.

  3. C3NeF is characteristic of membranoproliferative glomerulonephritis (type II).

  4. C3NeF is just a marker and is not directly pathogenic.

  5. C3NeF may be transferred across the placenta into the foetal circulation.
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

It is produced by plasma cells and B cells in the usual way.