Biology

Human Immunity and Blood

2,096 Questions

Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.

Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology

Human Immunity and Blood Questions

Multiple choice

Identify the false statements.

  1. Heat inactivation of serum is done to inactivate prions.
  2. Nude mice refer to transgenic mice.
  3. A humanised antibody is one in which the CDRs are from mouse and the rest is from human.
  4. B-lymphocytes originate from the bone marrow.

  1. 1 and 2

  2. 1 and 3

  3. 2 and 3

  4. 2 and 4

  5. 3 and 4
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Correct answer. Both are false statements. Heat-inactivation (heating to 56°C for 30 minutes) of serum is done to inactivate complement, a group of proteins present in sera that are part of the immune response. A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells.

Multiple choice

Which of the following skin cells possesses immune function?

  1. Keratocytes

  2. Melanocytes

  3. Langerhans cells

  4. Merkel cells
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

In skin infections, the local Langerhans cells take up and process microbial antigens to become fully functional antigen-presenting cells; thus it plays a major role in immunity.

Multiple choice

Human blood contains ________ percentage of plasma.

  1. 35%

  2. 40%

  3. 55%

  4. 65%
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Blood is a specialized bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells. In vertebrates, it is composed of blood cells suspended in a liquid called blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume),and contains dissipated proteins, glucose, mineral ions, hormones, carbon dioxide , and blood cells themselves 

Multiple choice

Which of the following statements regarding the ABO blood types is incorrect?

  1. Antibodies to alien antigens in the ABO group lies in plasma.

  2. Individuals having type A blood will have the A antigen on the surface of their red cells.

  3. The environment potentially can determine which blood types in a population will be passed on more frequently to the next generation.

  4. Individuals having O blood group cannot receive A, B and AB blood.

  5. ABO blood type antigens are found on the surface of red blood cells.
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

ABO blood type antigens are not only found on the surface of red cells. They are also normally secreted in their body fluids, including saliva, tears and urine.

Multiple choice

Red blood corpuscles are formed in the

  1. Bone marrow

  2. Liver

  3. Heart

  4. Kidneys
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Blood cells are made in the bone marrow. Erythrocytes, or red blood cells, are constantly being produced and released from marrow tissue. Leukocytes, or white blood cells are also produced in the bone marrow.