Biology
Human Immunity and Blood
2,096 Questions
Human immunity and blood questions cover the physiological mechanisms protecting the body against diseases and the components of blood. Topics include blood groups, cell mediated immunity, monoclonal antibodies, and blood coagulation. These biology topics frequently appear in general science sections of competitive exams.
Blood groupsCell mediated immunityMonoclonal antibodiesBlood coagulationCancer immunology
Human Immunity and Blood Questions
Which of the following is NOT a type of cytokine?
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Interleukins
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Interferons
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Antibodies
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Tumor necrosis factor
C
Correct answer
Explanation
Antibodies are produced by B cells and plasma cells, and they are not considered to be cytokines.
Which cytokine is responsible for stimulating the differentiation of T helper cells?
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Interleukin-2
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Interleukin-4
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Interleukin-6
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Interleukin-10
A
Correct answer
Explanation
Interleukin-2 is a cytokine that is produced by activated T cells and other immune cells. It stimulates the differentiation of T helper cells, which are important for coordinating immune responses.
Which cytokine is responsible for inhibiting the production of pro-inflammatory cytokines?
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Interleukin-10
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Interleukin-12
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Interleukin-18
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Interleukin-22
A
Correct answer
Explanation
Interleukin-10 is a cytokine that is produced by regulatory T cells and other immune cells. It inhibits the production of pro-inflammatory cytokines, such as interleukin-1, interleukin-6, and tumor necrosis factor, and it promotes the production of anti-inflammatory cytokines, such as interleukin-4 and interleukin-10.
Which cytokine is responsible for stimulating the production of antibodies by B cells?
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Interleukin-4
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Interleukin-6
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Interleukin-10
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Interleukin-12
A
Correct answer
Explanation
Interleukin-4 is a cytokine that is produced by activated T helper cells and other immune cells. It stimulates the production of antibodies by B cells, and it also promotes the differentiation of B cells into plasma cells.
Which cytokine is responsible for stimulating the production of interferon-gamma by natural killer cells?
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Interleukin-12
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Interleukin-15
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Interleukin-18
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Interleukin-21
A
Correct answer
Explanation
Interleukin-12 is a cytokine that is produced by macrophages, dendritic cells, and other immune cells. It stimulates the production of interferon-gamma by natural killer cells, which are important for controlling viral infections and tumor growth.
Which cytokine is responsible for stimulating the production of tumor necrosis factor by macrophages?
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Interleukin-1
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Interleukin-6
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Interleukin-8
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Interleukin-10
A
Correct answer
Explanation
Interleukin-1 is a cytokine that is produced by macrophages, dendritic cells, and other immune cells. It stimulates the production of tumor necrosis factor by macrophages, which is important for controlling infections and promoting inflammation.
Which cytokine is responsible for stimulating the production of granulocyte-macrophage colony-stimulating factor by fibroblasts?
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Interleukin-3
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Interleukin-5
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Interleukin-6
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Interleukin-11
C
Correct answer
Explanation
Interleukin-6 is a cytokine that is produced by fibroblasts, macrophages, and other cells. It stimulates the production of granulocyte-macrophage colony-stimulating factor by fibroblasts, which is important for the production of neutrophils and macrophages.
Which cytokine is responsible for stimulating the production of erythropoietin by kidney cells?
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Interleukin-1
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Interleukin-3
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Interleukin-6
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Interleukin-11
B
Correct answer
Explanation
Interleukin-3 is a cytokine that is produced by activated T cells and other immune cells. It stimulates the production of erythropoietin by kidney cells, which is important for the production of red blood cells.
Which cytokine is responsible for stimulating the production of hepatocyte growth factor by hepatocytes?
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Interleukin-6
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Interleukin-11
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Interleukin-15
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Interleukin-21
A
Correct answer
Explanation
Interleukin-6 is a cytokine that is produced by hepatocytes, macrophages, and other cells. It stimulates the production of hepatocyte growth factor by hepatocytes, which is important for the regeneration of liver tissue.
Which cytokine is responsible for stimulating the production of platelet-derived growth factor by platelets?
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Interleukin-4
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Interleukin-6
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Interleukin-8
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Interleukin-10
A
Correct answer
Explanation
Interleukin-4 is a cytokine that is produced by activated T helper cells and other immune cells. It stimulates the production of platelet-derived growth factor by platelets, which is important for the healing of wounds.
Which cytokine is responsible for stimulating the production of vascular endothelial growth factor by endothelial cells?
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Interleukin-8
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Interleukin-10
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Interleukin-12
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Interleukin-15
A
Correct answer
Explanation
Interleukin-8 is a cytokine that is produced by macrophages, neutrophils, and other cells. It stimulates the production of vascular endothelial growth factor by endothelial cells, which is important for the growth of new blood vessels.
Which cytokine is responsible for stimulating the production of transforming growth factor-beta by T cells?
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Interleukin-10
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Interleukin-12
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Interleukin-18
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Interleukin-21
A
Correct answer
Explanation
Interleukin-10 is a cytokine that is produced by regulatory T cells and other immune cells. It stimulates the production of transforming growth factor-beta by T cells, which is important for the regulation of immune responses and the healing of wounds.
Which cytokine is responsible for stimulating the production of fibroblast growth factor by fibroblasts?
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Interleukin-1
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Interleukin-6
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Interleukin-8
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Interleukin-11
A
Correct answer
Explanation
Interleukin-1 is a cytokine that is produced by macrophages, dendritic cells, and other immune cells. It stimulates the production of fibroblast growth factor by fibroblasts, which is important for the healing of wounds and the growth of new tissue.
Which of the following is NOT a type of tumor antigen?
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Cancer-testis antigens
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Overexpressed self-antigens
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Mutated neoantigens
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Viral antigens
D
Correct answer
Explanation
Viral antigens are not typically considered tumor antigens, as they are associated with viral infections rather than cancer.
Which immune cell type is responsible for antigen presentation to T cells?
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B cells
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Macrophages
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Natural killer cells
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Dendritic cells
D
Correct answer
Explanation
Dendritic cells are specialized antigen-presenting cells that capture, process, and present antigens to T cells, initiating an immune response.