Multiple choice

Which of the following conditions occurs in immunodeficiency disease X-linked agammaglobulinemia?

  1. Normal number of B-cells with decreased IgG and IgA and increased IgM

  2. B-cells are present but with reduction in 2 or more isotypes

  3. Complete lack of antibodies

  4. Selective immunoglobulin A deficiency

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

In X-linked agammaglobulinemia, B-cells are not generated. Due to this, antibodies are not formed and it manifests as a complete lack of antibodies in their bloodstream. It happens due to a mutation in X-chromosome.