Multiple choice

Mutations in the gammac chain of the receptors for IL-2, 4, 7, 9 and 15 can lead to which of the following diseases?

  1. Reticular dysgenesis

  2. Bare lymphocyte syndrome

  3. Hyper-IgM syndrome

  4. Severe combined immunodeficiency

  5. Build-up of toxic nucleotide metabolites

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

In particular, the receptor for IL-7 is the most crucial for lymphocyte differentiation.