Multiple choice

Which of the following syndromes arises due to mutation in the TP53 tumor suppressor gene?

  1. Cowden syndrome

  2. Li-Fraumeni syndrome

  3. Hereditary breast and ovarian cancer

  4. Hereditary non-polyposis colon cancer (HNPCC)

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

It is an autosomal dominant disease. It arises due to the mutation in the TP53 tumor suppressor gene. Its symptom includes cancers involving multiple sites including soft tissue sarcoma, osteosarcoma, etc.