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  • Medical Biology: Oncology and Renal Physiology
  • The majority of ovarian epithelial cancers occurring on a...
Multiple choice

The majority of ovarian epithelial cancers occurring on a hereditary basis originates in a woman with germline mutations in which gene?

  1. BRCA 2

  2. BRCA 1

  3. p53

  4. MSH2

  5. pRb

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Mutations in the BRCA 1 gene (located on chromosome 17) cause most of the ovarian epithelial cancers seen on a hereditary basis.

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